Assessing predicted HIV-1 replicative capacity in a clinical setting.
HIV-1 replicative capacity (RC) provides a measure of within-host fitness and is determined in the context of phenotypic drug resistance testing. However it is unclear how these in-vitro measurements relate to in-vivo processes. Here we assess RCs in a clinical setting by combining a previously publ...
Main Authors: | Roger D Kouyos, Viktor von Wyl, Trevor Hinkley, Christos J Petropoulos, Mojgan Haddad, Jeannette M Whitcomb, Jürg Böni, Sabine Yerly, Cristina Cellerai, Thomas Klimkait, Huldrych F Günthard, Sebastian Bonhoeffer, Swiss HIV Cohort Study |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-11-01
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Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22072960/pdf/?tool=EBI |
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