Comparison of clinical significance between optical coherence tomography guided percutaneous coronary intervention and angiography-guided percutaneous coronary intervention in acute coronary syndrome of the south zone of Tamil Nadu
Background: Intravascular optical coherence tomography (OCT) has specific features favoring its utilization in acute coronary syndrome (ACS). OCT has 100% sensitivity for detecting intraluminal thrombus compared to conventional coronary angiograms. Aims and Objectives: This study compares the cli...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Manipal College of Medical Sciences, Pokhara
2023-10-01
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| Series: | Asian Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://www.nepjol.info/index.php/AJMS/article/view/54010 |
| Summary: | Background: Intravascular optical coherence tomography (OCT) has specific features favoring its utilization in acute coronary syndrome (ACS). OCT has 100% sensitivity for detecting intraluminal thrombus compared to conventional coronary angiograms.
Aims and Objectives: This study compares the clinical significance of OCT findings during percutaneous coronary intervention (PCI) and angiography-guided PCI in ACS patients.
Materials and Methods: This prospective observational study was conducted in a tertiary care cardiac center at Tirunelveli Medical College Hospital and included 43 patients who had undergone both conventional and OCT-guided stenting (PCI) coronary angiograms. Their pre- and post-stenting findings of Intravascular OCT, conventional angiogram findings, and follow-up coronary angiogram findings were recorded.
Results: The mean age of the patients was 51.61 years, with 20 (87%) males and 19 (86.4%) males in the OCT-guided PCI group. Baseline risk factors such as hypertension, smoking, and T2DM were noted. Pre-OCT showed fibrofatty plaque, plaque rupture, red thrombus, spotty calcium, mixed thrombus, and white thrombus. Post-stenting OCT results showed 13.6% Edge dissection, 9.1% Malapposition, 9.1% Red thrombus, 4.5% Tissue prolapse, and 4.5% white thrombus. Five patients had chest pain on follow-up; a check angiogram showed stent thrombosis and restenosis in four cases (17.4%), and reintervention was done. One case of early stent thrombosis expired, which is statistically significant.
Conclusion: Intravascular OCT is a promising new and advanced technology for intra-coronary imaging due to its high resolution and dynamic range. |
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| ISSN: | 2467-9100 2091-0576 |