Synaptic Release Potentiation at Aging Auditory Ribbon Synapses

Synaptic Release Potentiation at Aging Auditory Ribbon Synapses

Age-related hidden hearing loss is often described as a cochlear synaptopathy that results from a progressive degeneration of the inner hair cell (IHC) ribbon synapses. The functional changes occurring at these synapses during aging are not fully understood. Here, we characterized this aging process...

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Bibliographic Details
Main Authors: Thibault Peineau, Séverin Belleudy, Susanna Pietropaolo, Yohan Bouleau, Didier Dulon
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Aging Neuroscience
Subjects:
auditory hair cells
synaptic ribbons
synaptopathy
hyperacusis
Ca2+ channels
exocytosis
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2021.756449/full

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