Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS)
Periodontitis is a common chronic inflammatory disease which could have an important impact on blood pressure (BP). This study aimed to explore (a) the association between periodontal health and BP in a large representative cohort, (b) the predictive value of diagnosis of periodontitis in undiagnose...
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| Format: | Article |
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MDPI AG
2020-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/9/5/1585 |
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| author | Vanessa Machado Eva Muñoz Aguilera João Botelho Syed Basit Hussain Yago Leira Luís Proença Francesco D’Aiuto José João Mendes |
| author_facet | Vanessa Machado Eva Muñoz Aguilera João Botelho Syed Basit Hussain Yago Leira Luís Proença Francesco D’Aiuto José João Mendes |
| author_sort | Vanessa Machado |
| collection | DOAJ |
| description | Periodontitis is a common chronic inflammatory disease which could have an important impact on blood pressure (BP). This study aimed to explore (a) the association between periodontal health and BP in a large representative cohort, (b) the predictive value of diagnosis of periodontitis in undiagnosed raised BP and (c) whether age is a mediator of this relationship. In total, 1057 randomly recruited individuals (mean age, 60.9 ± 16.3 years, 57.7% women) underwent periodontal clinical assessment and one-single BP measurement using an automated sphygmomanometer device. Logistic and linear regression models were used to estimate the odds of hypertension based on periodontitis case definitions. Mediation analysis was performed to understand the effect of age on the association of periodontitis with hypertension. Adjusted logistic model for gender, smoking habits and body mass index confirmed the association between high BP and periodontitis (OR = 2.31, 95%CI: 1.75–3.04, <i>p</i> < 0.001). Among 168 participants with undiagnosed high BP (15.9% of the study sample), 62.5% had periodontitis (<i>n</i> = 105). In this study, the association between periodontitis with both systolic blood pressure (SBP) (77.6%, <i>p</i> < 0.001) and diastolic blood pressure (DBP) (66.0%, <i>p</i> < 0.001) was mediated by age. Periodontitis is closely linked to BP in a representative Portuguese population. |
| first_indexed | 2024-03-10T19:38:54Z |
| format | Article |
| id | doaj.art-ac66c1ddcd8e43a1bb14534de599fe25 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T19:38:54Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-ac66c1ddcd8e43a1bb14534de599fe252023-11-20T01:29:10ZengMDPI AGJournal of Clinical Medicine2077-03832020-05-0195158510.3390/jcm9051585Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS)Vanessa Machado0Eva Muñoz Aguilera1João Botelho2Syed Basit Hussain3Yago Leira4Luís Proença5Francesco D’Aiuto6José João Mendes7Periodontology Department, Clinical Research Unit (CRU), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz (IUEM), 2829-511 Caparica, PortugalPeriodontology Unit, University College London Eastman Dental Institute, 21 University Street, London WC1E 6DE, UKPeriodontology Department, Clinical Research Unit (CRU), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz (IUEM), 2829-511 Caparica, PortugalPeriodontology Unit, University College London Eastman Dental Institute, 21 University Street, London WC1E 6DE, UKPeriodontology Unit, University College London Eastman Dental Institute, 21 University Street, London WC1E 6DE, UKQuantitative Methods for Health Research (MQIS), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz (IUEM), 2829-511 Caparica, PortugalPeriodontology Unit, University College London Eastman Dental Institute, 21 University Street, London WC1E 6DE, UKClinical Research Unit (CRU), Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), Instituto Universitário Egas Moniz (IUEM), 2829-511 Caparica, PortugalPeriodontitis is a common chronic inflammatory disease which could have an important impact on blood pressure (BP). This study aimed to explore (a) the association between periodontal health and BP in a large representative cohort, (b) the predictive value of diagnosis of periodontitis in undiagnosed raised BP and (c) whether age is a mediator of this relationship. In total, 1057 randomly recruited individuals (mean age, 60.9 ± 16.3 years, 57.7% women) underwent periodontal clinical assessment and one-single BP measurement using an automated sphygmomanometer device. Logistic and linear regression models were used to estimate the odds of hypertension based on periodontitis case definitions. Mediation analysis was performed to understand the effect of age on the association of periodontitis with hypertension. Adjusted logistic model for gender, smoking habits and body mass index confirmed the association between high BP and periodontitis (OR = 2.31, 95%CI: 1.75–3.04, <i>p</i> < 0.001). Among 168 participants with undiagnosed high BP (15.9% of the study sample), 62.5% had periodontitis (<i>n</i> = 105). In this study, the association between periodontitis with both systolic blood pressure (SBP) (77.6%, <i>p</i> < 0.001) and diastolic blood pressure (DBP) (66.0%, <i>p</i> < 0.001) was mediated by age. Periodontitis is closely linked to BP in a representative Portuguese population.https://www.mdpi.com/2077-0383/9/5/1585hypertensionblood pressuresystolic blood pressurediastolic blood pressureperiodontitisperiodontal diseases |
| spellingShingle | Vanessa Machado Eva Muñoz Aguilera João Botelho Syed Basit Hussain Yago Leira Luís Proença Francesco D’Aiuto José João Mendes Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) Journal of Clinical Medicine hypertension blood pressure systolic blood pressure diastolic blood pressure periodontitis periodontal diseases |
| title | Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) |
| title_full | Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) |
| title_fullStr | Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) |
| title_full_unstemmed | Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) |
| title_short | Association between Periodontitis and High Blood Pressure: Results from the Study of Periodontal Health in Almada-Seixal (SoPHiAS) |
| title_sort | association between periodontitis and high blood pressure results from the study of periodontal health in almada seixal sophias |
| topic | hypertension blood pressure systolic blood pressure diastolic blood pressure periodontitis periodontal diseases |
| url | https://www.mdpi.com/2077-0383/9/5/1585 |
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