Topical anesthesia

Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can b...

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Main Authors: Mritunjay Kumar, Rajiv Chawla, Manish Goyal
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Journal of Anaesthesiology Clinical Pharmacology
Subjects:
Online Access:http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=4;spage=450;epage=456;aulast=Kumar
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author Mritunjay Kumar
Rajiv Chawla
Manish Goyal
author_facet Mritunjay Kumar
Rajiv Chawla
Manish Goyal
author_sort Mritunjay Kumar
collection DOAJ
description Topical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects.
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spelling doaj.art-ac68dd5ef410435b9ed94dc8de84d7e02022-12-22T02:46:37ZengWolters Kluwer Medknow PublicationsJournal of Anaesthesiology Clinical Pharmacology0970-91852015-01-0131445045610.4103/0970-9185.169049Topical anesthesiaMritunjay KumarRajiv ChawlaManish GoyalTopical anesthetics are being widely used in numerous medical and surgical sub-specialties such as anesthesia, ophthalmology, otorhinolaryngology, dentistry, urology, and aesthetic surgery. They cause superficial loss of pain sensation after direct application. Their delivery and effectiveness can be enhanced by using free bases; by increasing the drug concentration, lowering the melting point; by using physical and chemical permeation enhancers and lipid delivery vesicles. Various topical anesthetic agents available for use are eutectic mixture of local anesthetics, ELA-max, lidocaine, epinephrine, tetracaine, bupivanor, 4% tetracaine, benzocaine, proparacaine, Betacaine-LA, topicaine, lidoderm, S-caine patch™ and local anesthetic peel. While using them, careful attention must be paid to their pharmacology, area and duration of application, age and weight of the patients and possible side-effects.http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=4;spage=450;epage=456;aulast=KumarTopical anesthesiaEutectic mixture of local anestheticsiontophoresislocal anestheticskin permeation enhancersonophoresisuses and side-effects of topical anesthetics
spellingShingle Mritunjay Kumar
Rajiv Chawla
Manish Goyal
Topical anesthesia
Journal of Anaesthesiology Clinical Pharmacology
Topical anesthesia
Eutectic mixture of local anesthetics
iontophoresis
local anesthetic
skin permeation enhancer
sonophoresis
uses and side-effects of topical anesthetics
title Topical anesthesia
title_full Topical anesthesia
title_fullStr Topical anesthesia
title_full_unstemmed Topical anesthesia
title_short Topical anesthesia
title_sort topical anesthesia
topic Topical anesthesia
Eutectic mixture of local anesthetics
iontophoresis
local anesthetic
skin permeation enhancer
sonophoresis
uses and side-effects of topical anesthetics
url http://www.joacp.org/article.asp?issn=0970-9185;year=2015;volume=31;issue=4;spage=450;epage=456;aulast=Kumar
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