Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape
The WASP-family verprolin-homologous (Wave) complex enhances actin-related protein 2/3 (Arp2/3)-mediated actin polymerization. Recently, we have identified a novel Wave complex–actin–Wnt/β-catenin–Sox9 pathway that regulates epidermal morphogenesis and proliferation. These findings highlight a mecha...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2019-09-01
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| Series: | Molecular & Cellular Oncology |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/23723556.2019.1609877 |
| _version_ | 1797677161043197952 |
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| author | Jonathan Cohen Chen Luxenburg |
| author_facet | Jonathan Cohen Chen Luxenburg |
| author_sort | Jonathan Cohen |
| collection | DOAJ |
| description | The WASP-family verprolin-homologous (Wave) complex enhances actin-related protein 2/3 (Arp2/3)-mediated actin polymerization. Recently, we have identified a novel Wave complex–actin–Wnt/β-catenin–Sox9 pathway that regulates epidermal morphogenesis and proliferation. These findings highlight a mechanism by which actin polymerization impacts crucial signaling events in vivo. |
| first_indexed | 2024-03-11T22:41:03Z |
| format | Article |
| id | doaj.art-ac6a6923cee349f0989dac8e6fd6f34e |
| institution | Directory Open Access Journal |
| issn | 2372-3556 |
| language | English |
| last_indexed | 2024-03-11T22:41:03Z |
| publishDate | 2019-09-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Molecular & Cellular Oncology |
| spelling | doaj.art-ac6a6923cee349f0989dac8e6fd6f34e2023-09-22T09:11:00ZengTaylor & Francis GroupMolecular & Cellular Oncology2372-35562019-09-016510.1080/23723556.2019.16098771609877Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shapeJonathan Cohen0Chen Luxenburg1Tel Aviv UniversityTel Aviv UniversityThe WASP-family verprolin-homologous (Wave) complex enhances actin-related protein 2/3 (Arp2/3)-mediated actin polymerization. Recently, we have identified a novel Wave complex–actin–Wnt/β-catenin–Sox9 pathway that regulates epidermal morphogenesis and proliferation. These findings highlight a mechanism by which actin polymerization impacts crucial signaling events in vivo.http://dx.doi.org/10.1080/23723556.2019.1609877wave complexactin polymerizationwntsox9epidermis |
| spellingShingle | Jonathan Cohen Chen Luxenburg Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape Molecular & Cellular Oncology wave complex actin polymerization wnt sox9 epidermis |
| title | Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape |
| title_full | Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape |
| title_fullStr | Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape |
| title_full_unstemmed | Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape |
| title_short | Wave of the future: involvement of actin polymerization in the regulation of tissue growth and shape |
| title_sort | wave of the future involvement of actin polymerization in the regulation of tissue growth and shape |
| topic | wave complex actin polymerization wnt sox9 epidermis |
| url | http://dx.doi.org/10.1080/23723556.2019.1609877 |
| work_keys_str_mv | AT jonathancohen waveofthefutureinvolvementofactinpolymerizationintheregulationoftissuegrowthandshape AT chenluxenburg waveofthefutureinvolvementofactinpolymerizationintheregulationoftissuegrowthandshape |