Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review
Abstract Objective The aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy‐induced cardiomyopathy (CIC). Methods With the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic para...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2023-09-01
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| Series: | Annals of Noninvasive Electrocardiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/anec.13070 |
| _version_ | 1797693227121246208 |
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| author | Muhammad Shehram Hiba Khalid Hafiz Muhammad Shafique Bakht Umer Awais Zafar Asif Ullah Syed Muhammad Jawad Zaidi Jawad Basit Amin Mehmoodi Jahanzeb Malik |
| author_facet | Muhammad Shehram Hiba Khalid Hafiz Muhammad Shafique Bakht Umer Awais Zafar Asif Ullah Syed Muhammad Jawad Zaidi Jawad Basit Amin Mehmoodi Jahanzeb Malik |
| author_sort | Muhammad Shehram |
| collection | DOAJ |
| description | Abstract Objective The aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy‐induced cardiomyopathy (CIC). Methods With the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic parameters, and New York Heart Classification (NYHA) class was assessed through this qualitative systematic review. Results The five studies included a total of 169 patients who underwent CRT after CIC, and of these, 61 (36.1%) patients were males. All studies showed an improvement in left ventricular ejection fraction (LVEF), among other echocardiographic parameters of LV volume. However, these findings are limited by short follow‐up periods, small sample sizes, and the absence of a control group. Conclusion CRT was associated with improvement in all patient parameters with CIC. |
| first_indexed | 2024-03-12T02:40:30Z |
| format | Article |
| id | doaj.art-ac70d436c4ef4fd68143f04a643f9722 |
| institution | Directory Open Access Journal |
| issn | 1082-720X 1542-474X |
| language | English |
| last_indexed | 2024-03-12T02:40:30Z |
| publishDate | 2023-09-01 |
| publisher | Wiley |
| record_format | Article |
| series | Annals of Noninvasive Electrocardiology |
| spelling | doaj.art-ac70d436c4ef4fd68143f04a643f97222023-09-04T07:18:39ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2023-09-01285n/an/a10.1111/anec.13070Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic reviewMuhammad Shehram0Hiba Khalid1Hafiz Muhammad Shafique2Bakht Umer3Awais Zafar4Asif Ullah5Syed Muhammad Jawad Zaidi6Jawad Basit7Amin Mehmoodi8Jahanzeb Malik9Department of Cardiology Mufti Mehmood Memorial Teaching Hospital DI Khan PakistanDepartment of Dermatology Benazir Bhutto Hospital Rawalpindi PakistanDepartment of Interventional Cardiology Armed Forces Institute of Cardiology Rawalpindi PakistanDepartment of Interventional Cardiology Armed Forces Institute of Cardiology Rawalpindi PakistanDepartment of Medicine Sahiwal Medical College Sahiwal PakistanDepartment of Cardiology Khyber Medical University Institute of Medical Sciences Kohat PakistanDepartment of Cardiovascular Medicine Cardiovascular Analytics Group Canterbury UKDepartment of Cardiovascular Medicine Cardiovascular Analytics Group Canterbury UKDepartment of Medicine Ibn e Seen Hospital Kabul AfghanistanDepartment of Cardiovascular Medicine Cardiovascular Analytics Group Canterbury UKAbstract Objective The aim of the study was to assess the efficacy of cardiac resynchronization therapy (CRT) in patients with chemotherapy‐induced cardiomyopathy (CIC). Methods With the increasing incidence of CIC, the association of CRT with improvement in clinical outcomes, echocardiographic parameters, and New York Heart Classification (NYHA) class was assessed through this qualitative systematic review. Results The five studies included a total of 169 patients who underwent CRT after CIC, and of these, 61 (36.1%) patients were males. All studies showed an improvement in left ventricular ejection fraction (LVEF), among other echocardiographic parameters of LV volume. However, these findings are limited by short follow‐up periods, small sample sizes, and the absence of a control group. Conclusion CRT was associated with improvement in all patient parameters with CIC.https://doi.org/10.1111/anec.13070anthracyclinediastolic dysfunctionejection fractionheart failure |
| spellingShingle | Muhammad Shehram Hiba Khalid Hafiz Muhammad Shafique Bakht Umer Awais Zafar Asif Ullah Syed Muhammad Jawad Zaidi Jawad Basit Amin Mehmoodi Jahanzeb Malik Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review Annals of Noninvasive Electrocardiology anthracycline diastolic dysfunction ejection fraction heart failure |
| title | Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review |
| title_full | Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review |
| title_fullStr | Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review |
| title_full_unstemmed | Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review |
| title_short | Efficacy and safety of cardiac resynchronization therapy in chemotherapy‐induced cardiomyopathy: A systematic review |
| title_sort | efficacy and safety of cardiac resynchronization therapy in chemotherapy induced cardiomyopathy a systematic review |
| topic | anthracycline diastolic dysfunction ejection fraction heart failure |
| url | https://doi.org/10.1111/anec.13070 |
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