Current progress of source control in the management of intra-abdominal infections
Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-12-01
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| Series: | Chinese Journal of Traumatology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1008127520301668 |
| _version_ | 1818954164371193856 |
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| author | Xiu-Wen Wu Tao Zheng Zhi-Wu Hong Hua-Jian Ren Lei Wu Ge-Fei Wang Guo-Sheng Gu Jian-An Ren |
| author_facet | Xiu-Wen Wu Tao Zheng Zhi-Wu Hong Hua-Jian Ren Lei Wu Ge-Fei Wang Guo-Sheng Gu Jian-An Ren |
| author_sort | Xiu-Wen Wu |
| collection | DOAJ |
| description | Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pursuing source control. This last item makes abdominal sepsis a unique treatment challenge. Delayed or inadequate source control is an independent predictor of poor outcomes and recognizing source control failure is often difficult or impossible. Further complicating issue in the debate is surrounding the timing, adequacy, and procedures of source control. This review evaluated and summarized the current approach and challenges in IAI management, which are the future research directions. |
| first_indexed | 2024-12-20T10:17:49Z |
| format | Article |
| id | doaj.art-ac740ed2da484aeb917cc096e3e46a6e |
| institution | Directory Open Access Journal |
| issn | 1008-1275 |
| language | English |
| last_indexed | 2024-12-20T10:17:49Z |
| publishDate | 2020-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Chinese Journal of Traumatology |
| spelling | doaj.art-ac740ed2da484aeb917cc096e3e46a6e2022-12-21T19:44:01ZengElsevierChinese Journal of Traumatology1008-12752020-12-01236311313Current progress of source control in the management of intra-abdominal infectionsXiu-Wen Wu0Tao Zheng1Zhi-Wu Hong2Hua-Jian Ren3Lei Wu4Ge-Fei Wang5Guo-Sheng Gu6Jian-An Ren7Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, ChinaResearch Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China; Lab for Trauma and Surgical Infection, Jinling Hospital, Nanjing, China; Corresponding author.Intra-abdominal infection (IAI) is a deadly condition in which the outcome is associated with urgent diagnosis, assessment and management, including fluid resuscitation, antibiotic administration while obtaining further laboratory results, attaining precise measurements of hemodynamic status, and pursuing source control. This last item makes abdominal sepsis a unique treatment challenge. Delayed or inadequate source control is an independent predictor of poor outcomes and recognizing source control failure is often difficult or impossible. Further complicating issue in the debate is surrounding the timing, adequacy, and procedures of source control. This review evaluated and summarized the current approach and challenges in IAI management, which are the future research directions.http://www.sciencedirect.com/science/article/pii/S1008127520301668Source controlIntra-abdominal infectionOpen abdomenSource control failure |
| spellingShingle | Xiu-Wen Wu Tao Zheng Zhi-Wu Hong Hua-Jian Ren Lei Wu Ge-Fei Wang Guo-Sheng Gu Jian-An Ren Current progress of source control in the management of intra-abdominal infections Chinese Journal of Traumatology Source control Intra-abdominal infection Open abdomen Source control failure |
| title | Current progress of source control in the management of intra-abdominal infections |
| title_full | Current progress of source control in the management of intra-abdominal infections |
| title_fullStr | Current progress of source control in the management of intra-abdominal infections |
| title_full_unstemmed | Current progress of source control in the management of intra-abdominal infections |
| title_short | Current progress of source control in the management of intra-abdominal infections |
| title_sort | current progress of source control in the management of intra abdominal infections |
| topic | Source control Intra-abdominal infection Open abdomen Source control failure |
| url | http://www.sciencedirect.com/science/article/pii/S1008127520301668 |
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