Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties

Thioquinoline derivatives conjugated to thiosemicarbazide as potent tyrosinase inhibitors with anti-melanogenesis properties

Abstract In the present study, a series of aryl-substituted thioqunoline conjugated to thiosemicarbazide were rationally designed and synthesized. The formation of target compounds was confirmed by spectral characterization techniques such as IR, 1H-NMR, 13C-NMR, ESI–MS, and elemental analysis. Amon...

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Bibliographic Details
Main Authors: Milad Noori, Reyhaneh Sabourian, Ali Tasharoie, Maliheh Safavi, Aida Iraji, Minoo Khalili Ghomi, Navid Dastyafteh, Cambyz Irajie, Elham Zarenezhad, Seyyed Mehrdad Mostafavi Pour, Fatemeh Rasekh, Bagher Larijani, Mohsen Amini, Mannan Hajimahmoodi, Mohammad Mahdavi
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28852-1

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