Randomization Tests that Condition on Non-Categorical Covariate Balance

A benefit of randomized experiments is that covariate distributions of treatment and control groups are balanced on average, resulting in simple unbiased estimators for treatment effects. However, it is possible that a particular randomization yields covariate imbalances that researchers want to add...

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Main Authors: Branson Zach, Miratrix Luke W.
Format: Article
Language:English
Published: De Gruyter 2019-04-01
Series:Journal of Causal Inference
Subjects:
Online Access:https://doi.org/10.1515/jci-2018-0004
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author Branson Zach
Miratrix Luke W.
author_facet Branson Zach
Miratrix Luke W.
author_sort Branson Zach
collection DOAJ
description A benefit of randomized experiments is that covariate distributions of treatment and control groups are balanced on average, resulting in simple unbiased estimators for treatment effects. However, it is possible that a particular randomization yields covariate imbalances that researchers want to address in the analysis stage through adjustment or other methods. Here we present a randomization test that conditions on covariate balance by only considering treatment assignments that are similar to the observed one in terms of covariate balance. Previous conditional randomization tests have only allowed for categorical covariates, while our randomization test allows for any type of covariate. Through extensive simulation studies, we find that our conditional randomization test is more powerful than unconditional randomization tests and other conditional tests. Furthermore, we find that our conditional randomization test is valid (1) unconditionally across levels of covariate balance, and (2) conditional on particular levels of covariate balance. Meanwhile, unconditional randomization tests are valid for (1) but not (2). Finally, we find that our conditional randomization test is similar to a randomization test that uses a model-adjusted test statistic.
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spelling doaj.art-ac75976270654c0b8729ef73638560952022-12-21T21:26:48ZengDe GruyterJournal of Causal Inference2193-36772193-36852019-04-01711355410.1515/jci-2018-0004Randomization Tests that Condition on Non-Categorical Covariate BalanceBranson Zach0Miratrix Luke W.1Department of Statistics, Harvard University, Cambridge, Massachusetts, United StatesGraduate School of Education and Department of Statistics, Harvard University, Cambridge, Massachusetts, United StatesA benefit of randomized experiments is that covariate distributions of treatment and control groups are balanced on average, resulting in simple unbiased estimators for treatment effects. However, it is possible that a particular randomization yields covariate imbalances that researchers want to address in the analysis stage through adjustment or other methods. Here we present a randomization test that conditions on covariate balance by only considering treatment assignments that are similar to the observed one in terms of covariate balance. Previous conditional randomization tests have only allowed for categorical covariates, while our randomization test allows for any type of covariate. Through extensive simulation studies, we find that our conditional randomization test is more powerful than unconditional randomization tests and other conditional tests. Furthermore, we find that our conditional randomization test is valid (1) unconditionally across levels of covariate balance, and (2) conditional on particular levels of covariate balance. Meanwhile, unconditional randomization tests are valid for (1) but not (2). Finally, we find that our conditional randomization test is similar to a randomization test that uses a model-adjusted test statistic.https://doi.org/10.1515/jci-2018-0004conditional inferencecovariate adjustmentstatistical powervalidity
spellingShingle Branson Zach
Miratrix Luke W.
Randomization Tests that Condition on Non-Categorical Covariate Balance
Journal of Causal Inference
conditional inference
covariate adjustment
statistical power
validity
title Randomization Tests that Condition on Non-Categorical Covariate Balance
title_full Randomization Tests that Condition on Non-Categorical Covariate Balance
title_fullStr Randomization Tests that Condition on Non-Categorical Covariate Balance
title_full_unstemmed Randomization Tests that Condition on Non-Categorical Covariate Balance
title_short Randomization Tests that Condition on Non-Categorical Covariate Balance
title_sort randomization tests that condition on non categorical covariate balance
topic conditional inference
covariate adjustment
statistical power
validity
url https://doi.org/10.1515/jci-2018-0004
work_keys_str_mv AT bransonzach randomizationteststhatconditiononnoncategoricalcovariatebalance
AT miratrixlukew randomizationteststhatconditiononnoncategoricalcovariatebalance