Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity

Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity

BackgroundDipeptidyl peptidase 4 (DPP-4, also known as CD26) binds with adenosine deaminase (ADA) to activate T lymphocytes. Here, we investigated whether ADA activity is specifically affected by treatment with DPP-4 inhibitor (DPP4I) compared with other anti-diabetic agents.MethodsFasting ADA activ...

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Bibliographic Details
Main Authors:	Jae-Geun Lee, Dong Gu Kang, Jung Re Yu, Youngree Kim, Jinsoek Kim, Gwanpyo Koh, Daeho Lee
Format:	Article
Language:	English
Published:	Korean Diabetes Association 2011-04-01
Series:	Diabetes & Metabolism Journal
Subjects:	Adenosine deaminase Diabetes mellitus, type 2 Dipeptidyl peptidase
Online Access:	http://e-dmj.org/Synapse/Data/PDFData/2004DMJ/dmj-35-149.pdf

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