Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report
Adenosine deaminase (ADA) in cerebrospinal fluid (CSF) is considered to be a useful biomarker in differentiating tuberculous meningitis (TBM) from other meningitis in non-HIV patients. However, its specificity decreases in patients with HIV, and other diseases such as cytomegalovirus encephalitis, t...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2020-09-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971220304859 |
| _version_ | 1828421216185090048 |
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| author | Asako Doi Toshikazu Hasuike Tatsuya Shindo Hiroaki Nishioka |
| author_facet | Asako Doi Toshikazu Hasuike Tatsuya Shindo Hiroaki Nishioka |
| author_sort | Asako Doi |
| collection | DOAJ |
| description | Adenosine deaminase (ADA) in cerebrospinal fluid (CSF) is considered to be a useful biomarker in differentiating tuberculous meningitis (TBM) from other meningitis in non-HIV patients. However, its specificity decreases in patients with HIV, and other diseases such as cytomegalovirus encephalitis, toxoplasmosis or meningeal lymphomatosis can also elevate ADA in CSF. We here report a rare case of retroviral rebound syndrome in a HIV patient, whose ADA in CSF was elevated. |
| first_indexed | 2024-12-10T15:26:09Z |
| format | Article |
| id | doaj.art-ac798bb7a3ed4f6183d0baaf871f7cbe |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-10T15:26:09Z |
| publishDate | 2020-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-ac798bb7a3ed4f6183d0baaf871f7cbe2022-12-22T01:43:33ZengElsevierInternational Journal of Infectious Diseases1201-97122020-09-0198297298Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case reportAsako Doi0Toshikazu Hasuike1Tatsuya Shindo2Hiroaki Nishioka3Department of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, Japan; Corresponding author at: Department of infectious diseases, Kobe City Medical Center General Hospital, 650-0047, 2-1-1, Minamimachi, Minatojima, Chuo-ku, Kobe, Japan.Department of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, JapanDepartment of General Internal Medicine, Kobe City Medical Center General Hospital, JapanDepartment of Infectious Diseases, Kobe City Medical Center General Hospital, Japan; Department of General Internal Medicine, Kobe City Medical Center General Hospital, JapanAdenosine deaminase (ADA) in cerebrospinal fluid (CSF) is considered to be a useful biomarker in differentiating tuberculous meningitis (TBM) from other meningitis in non-HIV patients. However, its specificity decreases in patients with HIV, and other diseases such as cytomegalovirus encephalitis, toxoplasmosis or meningeal lymphomatosis can also elevate ADA in CSF. We here report a rare case of retroviral rebound syndrome in a HIV patient, whose ADA in CSF was elevated.http://www.sciencedirect.com/science/article/pii/S1201971220304859Adenosine deaminaseCerebrospinal fluidHuman immunodeficiency virusMeningitisRetroviral rebound syndrome |
| spellingShingle | Asako Doi Toshikazu Hasuike Tatsuya Shindo Hiroaki Nishioka Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report International Journal of Infectious Diseases Adenosine deaminase Cerebrospinal fluid Human immunodeficiency virus Meningitis Retroviral rebound syndrome |
| title | Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report |
| title_full | Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report |
| title_fullStr | Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report |
| title_full_unstemmed | Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report |
| title_short | Elevation of CSF adenosine deaminase in HIV patient with meningitis from retroviral rebound syndrome, a case report |
| title_sort | elevation of csf adenosine deaminase in hiv patient with meningitis from retroviral rebound syndrome a case report |
| topic | Adenosine deaminase Cerebrospinal fluid Human immunodeficiency virus Meningitis Retroviral rebound syndrome |
| url | http://www.sciencedirect.com/science/article/pii/S1201971220304859 |
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