Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4

Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4

Endoglin is a membrane glycoprotein primarily expressed by the vascular endothelium and involved in cardiovascular diseases. Upon the proteolytic processing of the membrane-bound protein, a circulating form of endoglin (soluble endoglin, sEng) can be released, and high levels of sEng have been obser...

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Bibliographic Details
Main Authors: Eunate Gallardo-Vara, Luis Gamella-Pozuelo, Lucía Perez-Roque, José L. Bartha, Irene Garcia-Palmero, J. Ignacio Casal, José M. López-Novoa, Miguel Pericacho, Carmelo Bernabeu
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
hypertension
preeclampsia
HHT
endoglin
endothelial cells
TGF-β
Online Access:https://www.mdpi.com/2073-4409/9/4/988

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