Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review

Astragalus improves intestinal barrier function and immunity by acting on intestinal microbiota to treat T2DM: a research review

Diabetes is a significant chronic endocrine/metabolism disorder that can result in a number of life-threatening consequences. According to research, the gut microbiota is strongly linked to the development of diabetes, making it a viable target for diabetes treatment. The intestinal microbiota affec...

Full description

Bibliographic Details
Main Authors:	Min Su, Ting Tang, Weiwei Tang, Yu Long, Lin Wang, Meiling Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-08-01
Series:	Frontiers in Immunology
Subjects:	Astragali Radix active ingredients type 2 diabetes mellitus intestinal microbiota immunity metabolism
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1243834/full

Similar Items

The “whole ingredients extract” of Astragali Radix improves the symptoms of dextran sulfate sodium-induced ulcerative colitis in mice through systemic immunomodulation
by: Ke-Gang Linghu, et al.
Published: (2022-09-01)

Review of the correlation between Chinese medicine and intestinal microbiota on the efficacy of diabetes mellitus
by: Min Su, et al.
Published: (2023-01-01)

Effect of Astragali radix extract on pharmacokinetic behavior of dapagliflozin in healthy and type 2 diabetic rats
by: Wandi Du, et al.
Published: (2023-10-01)

16S rRNA and Metagenomics Combined with UPLC-Q/TOF-MS Metabolomics Analysis Reveals the Potential Mechanism of Radix Astragali Against Hyperuricemia in Mice
by: Deng S, et al.
Published: (2023-05-01)

Isolating, Identifying, and Analyzing the Biological Characteristics of Pathogens Causing Postharvest Disease in Fresh <i>Radix Astragali</i>
by: Yuan Zhang, et al.
Published: (2023-09-01)

Research progress on the mechanism of TCM regulating intestinal microbiota in the treatment of DM mellitus
by: Yang Ping, et al.
Published: (2024-03-01)

RETRACTED: Astragali Radix Isoflavones Synergistically Alleviate Cerebral Ischemia and Reperfusion Injury Via Activating Estrogen Receptor-PI3K-Akt Signaling Pathway
by: Yong Gu, et al.
Published: (2021-02-01)

Neuroprotective effect of Astragali Radix on cerebral infarction based on proteomics
by: Ying Li, et al.
Published: (2023-06-01)

Effects of Astragali Radix on T lymphocyte subsets expression in peripheral blood of Hashimoto′s thyroiditis patients with normal thyroid function
by: LI Ziyun, et al.
Published: (2024-01-01)

Quantitative Evaluation of Twelve Major Components of Sulfur-Fumigated Astragali Radix with Different Durations by UPLC-MS
by: Xiaoyan Xing, et al.
Published: (2018-10-01)

Cysteine-rich peptide fingerprinting as a general method for herbal analysis to differentiate Radix Astragali and Radix Hedysarum
by: Huang, Jiayi, et al.
Published: (2020)

Exploring the In Vivo Existence Forms (23 Original Constituents and 147 Metabolites) of Astragali Radix Total Flavonoids and Their Distributions in Rats Using HPLC-DAD-ESI-IT-TOF-MS<sup>n</sup>
by: Li-Jia Liu, et al.
Published: (2020-11-01)

Formulation Optimization and Functional Evaluation of Immunomodulatory Teabags
by: Haixin LIU, et al.
Published: (2023-06-01)

Residue of Chlormequat and Regulatory Effects on the Specialized Metabolites of Astragali Radix
by: Honghan Qin, et al.
Published: (2023-09-01)

Potential Quality Evaluation Method for Radix Astragali Based on Sweetness Indicators
by: Ke Li, et al.
Published: (2015-02-01)

Exploring the potential mechanism of radix astragali against ischemic stroke based on network pharmacology and molecular docking
by: Yang Zhen, et al.
Published: (2022-05-01)

Astragaloside IV: A promising natural neuroprotective agent for neurological disorders
by: Min Yao, et al.
Published: (2023-03-01)

Editorial: Functional food ingredients and intestinal homeostasis
by: Bo Li, et al.
Published: (2023-07-01)

The regulation of intestinal microbiota and the intervention of Chinese herbal medicine in the treatment of ulcerative colitis
by: Wang Haiou, et al.
Published: (2024-03-01)

Comparative analysis of chemical profiles of Radix Astragali between ultrafine granular powder and sliced traditional material
by: Liang Cao, et al.
Published: (2022-01-01)

The Effect of Herb-acupunctures of Bojoongiggi-tang (Buzhongyiqi-tang), Ginseng Radix, and Astragali Radix on Immune Responses in Rats
by: Kim, Jung-Hun, et al.
Published: (2000-12-01)

Genetic diversity of the Chinese medicinal plant Astragali Radix based on transcriptome-derived SSR markers
by: Ming Jiang, et al.
Published: (2023-03-01)

Radix Rehmanniae Praeparata (Shu Dihuang) exerts neuroprotective effects on ICV-STZ-induced Alzheimer’s disease mice through modulation of INSR/IRS-1/AKT/GSK-3β signaling pathway and intestinal microbiota
by: Yunfang Su, et al.
Published: (2023-02-01)

Rapid Screening and Identification of BSA Bound Ligands from Radix astragali Using BSA Immobilized Magnetic Nanoparticles Coupled with HPLC-MS
by: Liangliang Liu, et al.
Published: (2016-11-01)

Effects of Physical Properties and Processing Methods on Astragaloside IV and Flavonoids Content in <i>Astragali radix</i>
by: Mei-Yin Chien, et al.
Published: (2022-01-01)

A specific SNP-based multiplex PCR assay for the simultaneous identification of two biological ingredients for the Chinese patent medicine, Danggui Buxue pill
by: Yinrong Liu, et al.
Published: (2023-05-01)

Mannose enhances intestinal immune barrier function and dextran sulfate sodium salt-induced colitis in mice by regulating intestinal microbiota
by: Yi Yang, et al.
Published: (2024-03-01)

Intestinal microbiota and health
by: Kamer Kalip, et al.
Published: (2018-05-01)

Protopine Alleviates Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Regulating Intestinal Microbiota
by: Meishan Yue, et al.
Published: (2023-07-01)

Combination of Radix Astragali and Safflower Promotes Angiogenesis in Rats with Ischemic Stroke via Silencing PTGS2
by: Shouchao Xu, et al.
Published: (2023-01-01)

Untapping the Potential of Astragaloside IV in the Battle Against Respiratory Diseases
by: Tan J, et al.
Published: (2023-07-01)

The Extracts and Major Compounds Derived from Astragali Radix Alter Mitochondrial Bioenergetics in Cultured Cardiomyocytes: Comparison of Various Polar Solvents and Compounds
by: Yun Huang, et al.
Published: (2018-05-01)

Study of the Mechanism of Astragali Radix in Treating Type 2 Diabetes Mellitus and Its Renal Protection Based on Enzyme Activity, Network Pharmacology, and Experimental Verification
by: Chunnan Li, et al.
Published: (2023-12-01)

An evaluation of Astragali Radix with different growth patterns and years, based on a new multidimensional comparison method
by: Yapeng Wang, et al.
Published: (2024-02-01)

Intestinal Microbiota in Sepsis
by: Tongwen Sun, et al.
Published: (2022-05-01)

Hedysari Radix Praeparata Cum Melle repairs impaired intestinal barrier function and alleviates colitis-associated colorectal cancer via remodeling gut microbiota and metabolism
by: Yugui Zhang, et al.
Published: (2023-09-01)

The Gut Barrier, Intestinal Microbiota, and Liver Disease: Molecular Mechanisms and Strategies to Manage
by: Julio Plaza-Díaz, et al.
Published: (2020-11-01)

Study on the biotransformation and activities of three isoflavone glycosides from Radix Astragali by human feces in vitro
by: Xin Liu, et al.
Published: (2023-08-01)

Xylanase improves the intestinal barrier function of Nile tilapia (Oreochromis niloticus) fed with soybean (Glycine max) meal
by: Tong Wang, et al.
Published: (2023-07-01)

Sanqi Oral Solution Ameliorates Renal Ischemia/Reperfusion Injury via Reducing Apoptosis and Enhancing Autophagy: Involvement of ERK/mTOR Pathways
by: Ruimin Tian, et al.
Published: (2020-09-01)