Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus
Background: HD-tDCS is capable to increase the focality of neuromodulation and has been recently applied to improve endurance performance in healthy subjects. Objective/hypothesis: Whether these putative advantages could be exploited in active subjects with type 1 diabetes mellitus (T1D) remains que...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Brain Stimulation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1935861X22002091 |
| _version_ | 1828131425853898752 |
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| author | Luca Filipas Gabriele Gallo Andrea Meloni Livio Luzi Roberto Codella |
| author_facet | Luca Filipas Gabriele Gallo Andrea Meloni Livio Luzi Roberto Codella |
| author_sort | Luca Filipas |
| collection | DOAJ |
| description | Background: HD-tDCS is capable to increase the focality of neuromodulation and has been recently applied to improve endurance performance in healthy subjects. Objective/hypothesis: Whether these putative advantages could be exploited in active subjects with type 1 diabetes mellitus (T1D) remains questionable. Methods: In a double-blind, randomized crossover order, 11 high-level cyclists (27 ± 4.3 years; weight: 65.5 ± 8.6 kg; height: 180 ± 8 cm; VO2peak: 67.5 ± 2.9 mL min−1 kg−1) with T1D underwent either HD-tDCS (F3, F4) or control (SHAM) and completed a constant-load trial (CLT) at 75% of the 2nd ventilatory threshold plus a 15-km cycling time-trial (TT). Results: After HD-tDCS, the total time to cover the TT was 3.8% faster (P < 0.01), associated with a higher mean power output (P < 0.01), and a higher rate of power/perception of effort (P < 0.01) and power/heart rate at iso-time (P < 0.05) than the SHAM condition. Physiological parameters during CLT and TT did not differ in both conditions. Conclusions: These findings suggest that upregulation of the prefrontal cortex could enhance endurance performance in high-level cyclists with T1D, without altering physiological and perceptual responses at moderate intensity. Present data open to future applications of HD-tDCS to a wider population of active T1D-subjects. |
| first_indexed | 2024-04-11T16:47:30Z |
| format | Article |
| id | doaj.art-ac817011c18741e1aac5a6858352df77 |
| institution | Directory Open Access Journal |
| issn | 1935-861X |
| language | English |
| last_indexed | 2024-04-11T16:47:30Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Stimulation |
| spelling | doaj.art-ac817011c18741e1aac5a6858352df772022-12-22T04:13:32ZengElsevierBrain Stimulation1935-861X2022-09-0115512921299Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitusLuca Filipas0Gabriele Gallo1Andrea Meloni2Livio Luzi3Roberto Codella4Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, Italy; Corresponding author. Department of Biomedical Sciences for Health, Università degli Studi di Milano, Via F.lli Cervi 93, 20090, Segrate, Milano, Italy.Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genoa, Genoa, Italy; Centro Polifunzionale di Scienze Motorie, University of Genoa, Genoa, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, ItalyDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; Department of Endocrinology, Nutrition and Metabolic Diseases, IRCCS MultiMedica, Milan, ItalyBackground: HD-tDCS is capable to increase the focality of neuromodulation and has been recently applied to improve endurance performance in healthy subjects. Objective/hypothesis: Whether these putative advantages could be exploited in active subjects with type 1 diabetes mellitus (T1D) remains questionable. Methods: In a double-blind, randomized crossover order, 11 high-level cyclists (27 ± 4.3 years; weight: 65.5 ± 8.6 kg; height: 180 ± 8 cm; VO2peak: 67.5 ± 2.9 mL min−1 kg−1) with T1D underwent either HD-tDCS (F3, F4) or control (SHAM) and completed a constant-load trial (CLT) at 75% of the 2nd ventilatory threshold plus a 15-km cycling time-trial (TT). Results: After HD-tDCS, the total time to cover the TT was 3.8% faster (P < 0.01), associated with a higher mean power output (P < 0.01), and a higher rate of power/perception of effort (P < 0.01) and power/heart rate at iso-time (P < 0.05) than the SHAM condition. Physiological parameters during CLT and TT did not differ in both conditions. Conclusions: These findings suggest that upregulation of the prefrontal cortex could enhance endurance performance in high-level cyclists with T1D, without altering physiological and perceptual responses at moderate intensity. Present data open to future applications of HD-tDCS to a wider population of active T1D-subjects.http://www.sciencedirect.com/science/article/pii/S1935861X22002091tDCSBrain stimulationPerformanceElite cyclingDiabetes |
| spellingShingle | Luca Filipas Gabriele Gallo Andrea Meloni Livio Luzi Roberto Codella Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus Brain Stimulation tDCS Brain stimulation Performance Elite cycling Diabetes |
| title | Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus |
| title_full | Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus |
| title_fullStr | Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus |
| title_full_unstemmed | Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus |
| title_short | Effects of bilateral dorsolateral prefrontal cortex high-definition transcranial direct-current stimulation on time-trial performance in cyclists with type 1 diabetes mellitus |
| title_sort | effects of bilateral dorsolateral prefrontal cortex high definition transcranial direct current stimulation on time trial performance in cyclists with type 1 diabetes mellitus |
| topic | tDCS Brain stimulation Performance Elite cycling Diabetes |
| url | http://www.sciencedirect.com/science/article/pii/S1935861X22002091 |
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