Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon
Background: Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to at least isoniazid and rifampicin. In Cameroon, the prevalence is estimated at 150 cases/100,000 inhabitants or 6000 cases out of an estimated population of 3 million. Objective: The aim of the present study was to det...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2022-01-01
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| Series: | International Journal of Mycobacteriology |
| Subjects: | |
| Online Access: | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2022;volume=11;issue=4;spage=356;epage=363;aulast=Cecile |
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| author | Djuikoue I Cecile Ndjip Ndjock S. Alex Nzenya D Joëlle Nana S Cedric Chounna T Noemy Wandji G Irene Mfongouot P Leila Ketchaji Alice Nguedia Assob J. Clement Pokam Thumamo D. Benjamin |
| author_facet | Djuikoue I Cecile Ndjip Ndjock S. Alex Nzenya D Joëlle Nana S Cedric Chounna T Noemy Wandji G Irene Mfongouot P Leila Ketchaji Alice Nguedia Assob J. Clement Pokam Thumamo D. Benjamin |
| author_sort | Djuikoue I Cecile |
| collection | DOAJ |
| description | Background: Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to at least isoniazid and rifampicin. In Cameroon, the prevalence is estimated at 150 cases/100,000 inhabitants or 6000 cases out of an estimated population of 3 million. Objective: The aim of the present study was to determine the risk factors associated with MDR-TB at Deido District Hospital located in the littoral region of Cameroon. Methods: This was a cross-sectional and analytical retrospective study. Our sample included all TB patients undergoing treatment at the Diagnostic and Treatment Center of the hospital from January 2019 to August 2020. Identified risk factors of MDR-TB were analyzed using the SPSS software version 20.0. Results: A total of 304 participants were enrolled with a predominance of 185 (60.8%) men. The average age was 35 years (29–43 years). About 122/304 (40%) of the patients suffered from MDR-TB. The significant factors associated with MDR-TB were occupation (adjusted odd ratio [aOR] = 61.46), monthly income (aOR = 0.11), history of TB (aOR = 5.3), alcohol consumption (aOR = 12.7); self-medication (aOR = 5.4) and consultation of traditional healers for any cure (aOR = 155.84). Conclusion: The emergence of MDR-TB associated with several risk factors in the study area is worrisome and can be prevented by improving the living conditions of patients and putting in place appropriate treatment strategies. |
| first_indexed | 2024-04-12T02:02:38Z |
| format | Article |
| id | doaj.art-ac833ccaef194df9a711513fc0bcd5d6 |
| institution | Directory Open Access Journal |
| issn | 2212-5531 2212-554X |
| language | English |
| last_indexed | 2024-04-12T02:02:38Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | International Journal of Mycobacteriology |
| spelling | doaj.art-ac833ccaef194df9a711513fc0bcd5d62022-12-22T03:52:38ZengWolters Kluwer Medknow PublicationsInternational Journal of Mycobacteriology2212-55312212-554X2022-01-0111435636310.4103/ijmy.ijmy_136_22Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – CameroonDjuikoue I CecileNdjip Ndjock S. AlexNzenya D JoëlleNana S CedricChounna T NoemyWandji G IreneMfongouot P LeilaKetchaji AliceNguedia Assob J. ClementPokam Thumamo D. BenjaminBackground: Multidrug-resistant tuberculosis (MDR-TB) is defined as resistance to at least isoniazid and rifampicin. In Cameroon, the prevalence is estimated at 150 cases/100,000 inhabitants or 6000 cases out of an estimated population of 3 million. Objective: The aim of the present study was to determine the risk factors associated with MDR-TB at Deido District Hospital located in the littoral region of Cameroon. Methods: This was a cross-sectional and analytical retrospective study. Our sample included all TB patients undergoing treatment at the Diagnostic and Treatment Center of the hospital from January 2019 to August 2020. Identified risk factors of MDR-TB were analyzed using the SPSS software version 20.0. Results: A total of 304 participants were enrolled with a predominance of 185 (60.8%) men. The average age was 35 years (29–43 years). About 122/304 (40%) of the patients suffered from MDR-TB. The significant factors associated with MDR-TB were occupation (adjusted odd ratio [aOR] = 61.46), monthly income (aOR = 0.11), history of TB (aOR = 5.3), alcohol consumption (aOR = 12.7); self-medication (aOR = 5.4) and consultation of traditional healers for any cure (aOR = 155.84). Conclusion: The emergence of MDR-TB associated with several risk factors in the study area is worrisome and can be prevented by improving the living conditions of patients and putting in place appropriate treatment strategies.http://www.ijmyco.org/article.asp?issn=2212-5531;year=2022;volume=11;issue=4;spage=356;epage=363;aulast=Cecilecameroondoualalittoral regionmultidrug-resistant tuberculosisrisk factors |
| spellingShingle | Djuikoue I Cecile Ndjip Ndjock S. Alex Nzenya D Joëlle Nana S Cedric Chounna T Noemy Wandji G Irene Mfongouot P Leila Ketchaji Alice Nguedia Assob J. Clement Pokam Thumamo D. Benjamin Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon International Journal of Mycobacteriology cameroon douala littoral region multidrug-resistant tuberculosis risk factors |
| title | Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon |
| title_full | Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon |
| title_fullStr | Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon |
| title_full_unstemmed | Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon |
| title_short | Risk factors associated to multidrug-resistant tuberculosis in patients attending the deido district hospital of Douala – Cameroon |
| title_sort | risk factors associated to multidrug resistant tuberculosis in patients attending the deido district hospital of douala cameroon |
| topic | cameroon douala littoral region multidrug-resistant tuberculosis risk factors |
| url | http://www.ijmyco.org/article.asp?issn=2212-5531;year=2022;volume=11;issue=4;spage=356;epage=363;aulast=Cecile |
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