Efficacy of Topically Administered Dihydroartemisinin in Treating Papillomavirus-Induced Anogenital Dysplasia in Preclinical Mouse Models

Efficacy of Topically Administered Dihydroartemisinin in Treating Papillomavirus-Induced Anogenital Dysplasia in Preclinical Mouse Models

The artemisinin family of compounds is cytopathic in certain cancer cell lines that are positive for human papillomaviruses (HPV) and can potentially drive the regression of dysplastic lesions. We evaluated the efficacy of topical dihydroartemisinin (DHA) on cervical dysplasia and anal dysplasia in...

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Bibliographic Details
Main Authors: Laura C. Gunder, Simon Blaine-Sauer, Hillary R. Johnson, Myeong-Kyun Shin, Andrew S. Auyeung, Wei Zhang, Glen E. Leverson, Ella T. Ward-Shaw, Renee E. King, Stephanie M. McGregor, Kristina A. Matkowskyj, Paul F. Lambert, Evie H. Carchman
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Viruses
Subjects:
dihydroartemisinin
DHA
artemisinin
papillomavirus
HPV
MmuPV1
Online Access:https://www.mdpi.com/1999-4915/14/8/1632

Internet

https://www.mdpi.com/1999-4915/14/8/1632

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