Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

Cell type-specific and time-dependent light exposure contribute to silencing in neurons expressing Channelrhodopsin-2

Channelrhodopsin-2 (ChR2) has quickly gained popularity as a powerful tool for eliciting genetically targeted neuronal activation. However, little has been reported on the response kinetics of optogenetic stimulation across different neuronal subtypes. With excess stimulation, neurons can be driven...

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Bibliographic Details
Main Authors: Alexander M Herman, Longwen Huang, Dona K Murphey, Isabella Garcia, Benjamin R Arenkiel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2014-01-01
Series:eLife
Subjects:
optogenetics
action potential
in vivo
channelrhodopsin
silencing
Online Access:https://elifesciences.org/articles/01481

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