Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening

A 41-year-old woman with 2 previous failed IVF cycles was reported. After controlled ovarian hyperstimulation and then intracytoplasmic sperm injection (ICSI) of 4 metaphase II oocytes with ejaculated sperm was performed, 4 fertilized oocytes occurred. Two blastocysts were biopsied on day 5,...

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Main Authors: Jariya Lorwatthanasirikul, Wiwat Quangkananurug, Tosaporn Ruengkris, Sujin Chanchamroen, Surachai Pornwiroon, Nana Rayasawath
Format: Article
Language:English
Published: The Royal Thai College of Obstetricians and Gynaecologists 2012-09-01
Series:Thai Journal of Obstetrics and Gynaecology
Subjects:
Online Access:https://tci-thaijo.org/index.php/tjog/article/download/2955/2824/
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author Jariya Lorwatthanasirikul
Wiwat Quangkananurug
Tosaporn Ruengkris
Sujin Chanchamroen
Surachai Pornwiroon
Nana Rayasawath
author_facet Jariya Lorwatthanasirikul
Wiwat Quangkananurug
Tosaporn Ruengkris
Sujin Chanchamroen
Surachai Pornwiroon
Nana Rayasawath
author_sort Jariya Lorwatthanasirikul
collection DOAJ
description A 41-year-old woman with 2 previous failed IVF cycles was reported. After controlled ovarian hyperstimulation and then intracytoplasmic sperm injection (ICSI) of 4 metaphase II oocytes with ejaculated sperm was performed, 4 fertilized oocytes occurred. Two blastocysts were biopsied on day 5, one of them was chromosomally normal after array Comparative Genomic Hybridization (aCGH)-based preimplantation genetic screening (PGS). The successful pregnancy was achieved after blastocyst transfer. The aCGH-based PGS may be the preferred method to select the balanced and euploid embryo before transfer in IVF.
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spelling doaj.art-ac8dbedf599a43f593f8e3497db89b522022-12-21T18:34:36ZengThe Royal Thai College of Obstetricians and GynaecologistsThai Journal of Obstetrics and Gynaecology0857-60840857-60842012-09-01203121124Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic ScreeningJariya Lorwatthanasirikul0Wiwat Quangkananurug1Tosaporn Ruengkris2Sujin Chanchamroen3Surachai Pornwiroon4Nana Rayasawath5Safe Fertility and PGD Center, Bangkok, ThailandSafe Fertility and PGD Center, Bangkok, ThailandSafe Fertility and PGD Center, Bangkok, ThailandSafe Fertility and PGD Center, Bangkok, ThailandSafe Fertility and PGD Center, Bangkok, ThailandSafe Fertility and PGD Center, Bangkok, ThailandA 41-year-old woman with 2 previous failed IVF cycles was reported. After controlled ovarian hyperstimulation and then intracytoplasmic sperm injection (ICSI) of 4 metaphase II oocytes with ejaculated sperm was performed, 4 fertilized oocytes occurred. Two blastocysts were biopsied on day 5, one of them was chromosomally normal after array Comparative Genomic Hybridization (aCGH)-based preimplantation genetic screening (PGS). The successful pregnancy was achieved after blastocyst transfer. The aCGH-based PGS may be the preferred method to select the balanced and euploid embryo before transfer in IVF.https://tci-thaijo.org/index.php/tjog/article/download/2955/2824/PGSaCGHICSIrepeat IVF failure
spellingShingle Jariya Lorwatthanasirikul
Wiwat Quangkananurug
Tosaporn Ruengkris
Sujin Chanchamroen
Surachai Pornwiroon
Nana Rayasawath
Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
Thai Journal of Obstetrics and Gynaecology
PGS
aCGH
ICSI
repeat IVF failure
title Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
title_full Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
title_fullStr Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
title_full_unstemmed Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
title_short Successful Pregnancy Following ICSI Using Array Comparative Genomic Hybridization for Preimplantation Genetic Screening
title_sort successful pregnancy following icsi using array comparative genomic hybridization for preimplantation genetic screening
topic PGS
aCGH
ICSI
repeat IVF failure
url https://tci-thaijo.org/index.php/tjog/article/download/2955/2824/
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