The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation
Abstract Background Deformation imaging represents a method of measuring myocardial function, including global longitudinal strain (GLS), peak atrial longitudinal strain (PALS) and radial strain. This study aimed to assess subclinical improvements in left ventricular function in patients undergoing...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | Echo Research and Practice |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s44156-023-00017-w |
| _version_ | 1797864371466010624 |
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| author | Mark Coyle Gerard King Kathleen Bennett Andrew Maree Mark Hensey Stephen O’Connor Caroline Daly Gregory Murphy Ross T. Murphy |
| author_facet | Mark Coyle Gerard King Kathleen Bennett Andrew Maree Mark Hensey Stephen O’Connor Caroline Daly Gregory Murphy Ross T. Murphy |
| author_sort | Mark Coyle |
| collection | DOAJ |
| description | Abstract Background Deformation imaging represents a method of measuring myocardial function, including global longitudinal strain (GLS), peak atrial longitudinal strain (PALS) and radial strain. This study aimed to assess subclinical improvements in left ventricular function in patients undergoing transcatheter aortic valve implantation (TAVI) by comparing GLS, PALS and radial strain pre and post procedure. Methods We conducted a single site prospective observational study of 25 patients undergoing TAVI, comparing baseline and post-TAVI echocardiograms. Individual participants were assessed for differences in GLS, PALS and radial strain in addition to changes in left ventricular ejection fraction (LVEF) (%). Results Our results revealed a significant improvement in GLS (mean change pre-post of 2.14% [95% CI 1.08, 3.20] p = 0.0003) with no significant change in LVEF (0.96% [95% CI − 2.30, 4.22], p = 0.55). There was a statistically significant improvement in radial strain pre and post TAVI (mean 9.68% [95% CI 3.10, 16.25] p = 0.0058). There was positive trend towards improvements in PALS pre and post TAVI (mean change of 2.30% [95% CI − 0.19, 4.80] p = 0.068). Conclusion In patients undergoing TAVI, measuring GLS and radial strain provided statistically significant information regarding subclinical improvements in LV function, which may have prognostic implications. The incorporation of deformation imaging in addition to standard echocardiographic measurements may have an important role in guiding future management in patients undergoing TAVI and assessing response. |
| first_indexed | 2024-04-09T22:50:42Z |
| format | Article |
| id | doaj.art-ac8df27632974841803eab80abb36f18 |
| institution | Directory Open Access Journal |
| issn | 2055-0464 |
| language | English |
| last_indexed | 2024-04-09T22:50:42Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Echo Research and Practice |
| spelling | doaj.art-ac8df27632974841803eab80abb36f182023-03-22T11:39:19ZengBMCEcho Research and Practice2055-04642023-02-011011610.1186/s44156-023-00017-wThe use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantationMark Coyle0Gerard King1Kathleen Bennett2Andrew Maree3Mark Hensey4Stephen O’Connor5Caroline Daly6Gregory Murphy7Ross T. Murphy8Department of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalSchool of Population Health, Royal College of Surgeons Ireland, University of Medicine and HealthDepartment of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalDepartment of Cardiology, St James HospitalAbstract Background Deformation imaging represents a method of measuring myocardial function, including global longitudinal strain (GLS), peak atrial longitudinal strain (PALS) and radial strain. This study aimed to assess subclinical improvements in left ventricular function in patients undergoing transcatheter aortic valve implantation (TAVI) by comparing GLS, PALS and radial strain pre and post procedure. Methods We conducted a single site prospective observational study of 25 patients undergoing TAVI, comparing baseline and post-TAVI echocardiograms. Individual participants were assessed for differences in GLS, PALS and radial strain in addition to changes in left ventricular ejection fraction (LVEF) (%). Results Our results revealed a significant improvement in GLS (mean change pre-post of 2.14% [95% CI 1.08, 3.20] p = 0.0003) with no significant change in LVEF (0.96% [95% CI − 2.30, 4.22], p = 0.55). There was a statistically significant improvement in radial strain pre and post TAVI (mean 9.68% [95% CI 3.10, 16.25] p = 0.0058). There was positive trend towards improvements in PALS pre and post TAVI (mean change of 2.30% [95% CI − 0.19, 4.80] p = 0.068). Conclusion In patients undergoing TAVI, measuring GLS and radial strain provided statistically significant information regarding subclinical improvements in LV function, which may have prognostic implications. The incorporation of deformation imaging in addition to standard echocardiographic measurements may have an important role in guiding future management in patients undergoing TAVI and assessing response.https://doi.org/10.1186/s44156-023-00017-wAortic stenosisTAVIHeart failureLV strainReduced ejection fractionValve disease |
| spellingShingle | Mark Coyle Gerard King Kathleen Bennett Andrew Maree Mark Hensey Stephen O’Connor Caroline Daly Gregory Murphy Ross T. Murphy The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation Echo Research and Practice Aortic stenosis TAVI Heart failure LV strain Reduced ejection fraction Valve disease |
| title | The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| title_full | The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| title_fullStr | The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| title_full_unstemmed | The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| title_short | The use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| title_sort | use of deformation imaging in the assessment of patients pre and post transcatheter aortic valve implantation |
| topic | Aortic stenosis TAVI Heart failure LV strain Reduced ejection fraction Valve disease |
| url | https://doi.org/10.1186/s44156-023-00017-w |
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