Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study
<h4>Background</h4> Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. <h4>Objective</h4> In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with small-for-gestational age (SGA) and large-...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553085/?tool=EBI |
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| author | Salma Younes Muthanna Samara Noor Salama Rana Al-jurf Gheyath Nasrallah Sawsan Al-Obaidly Husam Salama Tawa Olukade Sara Hammuda Ghassan Abdoh Palli Valapila Abdulrouf Thomas Farrell Mai AlQubaisi Hilal Al Rifai Nader Al-Dewik |
| author_facet | Salma Younes Muthanna Samara Noor Salama Rana Al-jurf Gheyath Nasrallah Sawsan Al-Obaidly Husam Salama Tawa Olukade Sara Hammuda Ghassan Abdoh Palli Valapila Abdulrouf Thomas Farrell Mai AlQubaisi Hilal Al Rifai Nader Al-Dewik |
| author_sort | Salma Younes |
| collection | DOAJ |
| description | <h4>Background</h4> Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. <h4>Objective</h4> In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with small-for-gestational age (SGA) and large-for-gestational age (LGA) infants. <h4>Methods</h4> We performed a population-based retrospective study on 14,641 singleton live births registered in the PEARL-Peristat Study between April 2017 and March 2018 in Qatar. We estimated the incidence and examined the risk factors and outcomes using univariate and multivariate analysis. <h4>Results</h4> SGA and LGA incidence rates were 6.0% and 15.6%, respectively. In-hospital mortality among SGA and LGA infants was 2.5% and 0.3%, respectively, while for NICU admission or death in labor room and operation theatre was 28.9% and 14.9% respectively. Preterm babies were more likely to be born SGA (aRR, 2.31; 95% CI, 1.45–3.57) but male infants (aRR, 0.57; 95% CI, 0.4–0.81), those born to parous (aRR 0.66; 95% CI, 0.45–0.93), or overweight (aRR, 0.64; 95% CI, 0.42–0.97) mothers were less likely to be born SGA. On the other hand, males (aRR, 1.82; 95% CI, 1.49–2.19), infants born to parous mothers (aRR 2.16; 95% CI, 1.63–2.82), or to mothers with gestational diabetes mellitus (aRR 1.36; 95% CI, 1.11–1.66), or pre-gestational diabetes mellitus (aRR 2.58; 95% CI, 1.8–3.47) were significantly more likely to be LGA. SGA infants were at high risk of in-hospital mortality (aRR, 226.56; 95% CI, 3.47–318.22), neonatal intensive care unit admission or death in labor room or operation theatre (aRR, 2.14 (1.36–3.22). <h4>Conclusion</h4> Monitoring should be coordinated to alleviate the risks of inappropriate fetal growth and the associated adverse consequences. |
| first_indexed | 2024-12-17T13:45:09Z |
| format | Article |
| id | doaj.art-ac92080fca9a4115890787a68bbf60b8 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-17T13:45:09Z |
| publishDate | 2021-01-01 |
| publisher | Public Library of Science (PLoS) |
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| series | PLoS ONE |
| spelling | doaj.art-ac92080fca9a4115890787a68bbf60b82022-12-21T21:46:11ZengPublic Library of Science (PLoS)PLoS ONE1932-62032021-01-011610Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based studySalma YounesMuthanna SamaraNoor SalamaRana Al-jurfGheyath NasrallahSawsan Al-ObaidlyHusam SalamaTawa OlukadeSara HammudaGhassan AbdohPalli Valapila AbdulroufThomas FarrellMai AlQubaisiHilal Al RifaiNader Al-Dewik<h4>Background</h4> Abnormal fetal growth can be associated with factors during pregnancy and at postpartum. <h4>Objective</h4> In this study, we aimed to assess the incidence, risk factors, and feto-maternal outcomes associated with small-for-gestational age (SGA) and large-for-gestational age (LGA) infants. <h4>Methods</h4> We performed a population-based retrospective study on 14,641 singleton live births registered in the PEARL-Peristat Study between April 2017 and March 2018 in Qatar. We estimated the incidence and examined the risk factors and outcomes using univariate and multivariate analysis. <h4>Results</h4> SGA and LGA incidence rates were 6.0% and 15.6%, respectively. In-hospital mortality among SGA and LGA infants was 2.5% and 0.3%, respectively, while for NICU admission or death in labor room and operation theatre was 28.9% and 14.9% respectively. Preterm babies were more likely to be born SGA (aRR, 2.31; 95% CI, 1.45–3.57) but male infants (aRR, 0.57; 95% CI, 0.4–0.81), those born to parous (aRR 0.66; 95% CI, 0.45–0.93), or overweight (aRR, 0.64; 95% CI, 0.42–0.97) mothers were less likely to be born SGA. On the other hand, males (aRR, 1.82; 95% CI, 1.49–2.19), infants born to parous mothers (aRR 2.16; 95% CI, 1.63–2.82), or to mothers with gestational diabetes mellitus (aRR 1.36; 95% CI, 1.11–1.66), or pre-gestational diabetes mellitus (aRR 2.58; 95% CI, 1.8–3.47) were significantly more likely to be LGA. SGA infants were at high risk of in-hospital mortality (aRR, 226.56; 95% CI, 3.47–318.22), neonatal intensive care unit admission or death in labor room or operation theatre (aRR, 2.14 (1.36–3.22). <h4>Conclusion</h4> Monitoring should be coordinated to alleviate the risks of inappropriate fetal growth and the associated adverse consequences.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553085/?tool=EBI |
| spellingShingle | Salma Younes Muthanna Samara Noor Salama Rana Al-jurf Gheyath Nasrallah Sawsan Al-Obaidly Husam Salama Tawa Olukade Sara Hammuda Ghassan Abdoh Palli Valapila Abdulrouf Thomas Farrell Mai AlQubaisi Hilal Al Rifai Nader Al-Dewik Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study PLoS ONE |
| title | Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study |
| title_full | Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study |
| title_fullStr | Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study |
| title_full_unstemmed | Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study |
| title_short | Incidence, risk factors, and feto-maternal outcomes of inappropriate birth weight for gestational age among singleton live births in Qatar: A population-based study |
| title_sort | incidence risk factors and feto maternal outcomes of inappropriate birth weight for gestational age among singleton live births in qatar a population based study |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8553085/?tool=EBI |
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