Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment
Malignant mesothelioma (MM) is an asbestos related aggressive tumor with poor prognosis. The aim of this study was to investigate if aquaporin 1 (AQP1) genetic polymorphisms influence the risk of MM and the response to cisplatin based MM treatment.
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sciendo
2019-03-01
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| Series: | Radiology and Oncology |
| Subjects: | |
| Online Access: | https://doi.org/10.2478/raon-2019-0009 |
| _version_ | 1797848524107284480 |
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| author | Senk Barbara Goricar Katja Kovac Viljem Dolzan Vita Franko Alenka |
| author_facet | Senk Barbara Goricar Katja Kovac Viljem Dolzan Vita Franko Alenka |
| author_sort | Senk Barbara |
| collection | DOAJ |
| description | Malignant mesothelioma (MM) is an asbestos related aggressive tumor with poor prognosis. The aim of this study was to investigate if aquaporin 1 (AQP1) genetic polymorphisms influence the risk of MM and the response to cisplatin based MM treatment. |
| first_indexed | 2024-04-09T18:30:04Z |
| format | Article |
| id | doaj.art-ac927d36688a46ba91b206c7dc13eca2 |
| institution | Directory Open Access Journal |
| issn | 1581-3207 |
| language | English |
| last_indexed | 2024-04-09T18:30:04Z |
| publishDate | 2019-03-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Radiology and Oncology |
| spelling | doaj.art-ac927d36688a46ba91b206c7dc13eca22023-04-11T17:19:27ZengSciendoRadiology and Oncology1581-32072019-03-015319610410.2478/raon-2019-0009raon-2019-0009Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatmentSenk Barbara0Goricar Katja1Kovac Viljem2Dolzan Vita3Franko Alenka4Pharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaPharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaInstitute of Oncology Ljubljana, Ljubljana, SloveniaPharmacogenetics Laboratory, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana, Ljubljana, SloveniaClinical Institute of Occupational Medicine, University Medical Centre Ljubljana, Ljubljana, SloveniaMalignant mesothelioma (MM) is an asbestos related aggressive tumor with poor prognosis. The aim of this study was to investigate if aquaporin 1 (AQP1) genetic polymorphisms influence the risk of MM and the response to cisplatin based MM treatment.https://doi.org/10.2478/raon-2019-0009malignant mesotheliomaaqp1polymorphismcisplatin |
| spellingShingle | Senk Barbara Goricar Katja Kovac Viljem Dolzan Vita Franko Alenka Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment Radiology and Oncology malignant mesothelioma aqp1 polymorphism cisplatin |
| title | Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| title_full | Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| title_fullStr | Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| title_full_unstemmed | Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| title_short | Genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| title_sort | genetic polymorphisms in aquaporin 1 as risk factors for malignant mesothelioma and biomarkers of response to cisplatin treatment |
| topic | malignant mesothelioma aqp1 polymorphism cisplatin |
| url | https://doi.org/10.2478/raon-2019-0009 |
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