Chemical reactivity of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl)-2,4-dioxobutanoate towards some nucleophilic reagents

AbstractA novel series of heterocyclic systems linked with quinolin-2-one was efficiently synthesized from reaction of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl) -2,4-dioxobutanoate (1) with a variety of nitrogen and/or carbon nucleophiles. A variety of heterocyclic systems such as p...

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Bibliographic Details
Main Authors: Hany Hassanin, Magdi A. Ibrahim, Shimaa Badran
Format: Article
Language:English
Published: Turkish Chemical Society 2016-02-01
Series:Journal of the Turkish Chemical Society, Section A: Chemistry
Online Access:http://dergipark.gov.tr/jotcsa/issue/24619/260517?publisher=turchemsoc
Description
Summary:AbstractA novel series of heterocyclic systems linked with quinolin-2-one was efficiently synthesized from reaction of ethyl 4-(1-ethyl-1,2-dihydro-4-hydroxy-2-oxoquinolin-3-yl) -2,4-dioxobutanoate (1) with a variety of nitrogen and/or carbon nucleophiles. A variety of heterocyclic systems such as pyrazoles, pyrimidines, pyrazines, oxazines and triazines containing quinoline moiety were synthesized. Structures of the new synthesized products were deduced on basis of their analytical and spectral data.
ISSN:2149-0120