Cancer immunotherapy using γδT cells: dealing with diversity

Cancer immunotherapy using γδT cells: dealing with diversity

The broad and potent tumour-reactivity of innate-like γδT cells makes them valuable additions to current cancer immunotherapeutic concepts based on adaptive immunity, such as monoclonal antibodies and αβT cells. Clinical success using γδT cells to treat cancer has so far fallen short however. Effort...

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Bibliographic Details
Main Authors: Wouter eScheper, Zsolt eSebestyen, Jürgen eKuball
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Immunology
Subjects:
cancer immunotherapy
innate-like lymphocytes
γδT cells
γδT cell diversity
γδTCR
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00601/full

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