BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults

BNT162b2 booster after heterologous prime-boost vaccination induces potent neutralizing antibodies and T cell reactivity against SARS-CoV-2 Omicron BA.1 in young adults

In light of the decreasing immune protection against symptomatic SARS-CoV-2 infection after initial vaccinations and the now dominant immune-evasive Omicron variants, ‘booster’ vaccinations are regularly performed to restore immune responses. Many individuals have received a primary heterologous pri...

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Bibliographic Details
Main Authors: Alina Seidel, Michelle Zanoni, Rüdiger Groß, Daniela Krnavek, Sümeyye Erdemci-Evin, Pascal von Maltitz, Dan P. J. Albers, Carina Conzelmann, Sichen Liu, Tatjana Weil, Benjamin Mayer, Markus Hoffmann, Stefan Pöhlmann, Alexandra Beil, Joris Kroschel, Frank Kirchhoff, Jan Münch, Janis A. Müller
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
COVID-19
delta
B.1.1.529.1
BA.1
humoral immunity
memory T cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.882918/full

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