Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy

Inhibition of the lncRNA MIAT prevents podocyte injury and mitotic catastrophe in diabetic nephropathy

Podocyte damage is strongly associated with the progression of diabetic nephropathy. Mitotic catastrophe plays an essential role in accelerating podocyte loss and detachment from the glomerular basement membrane. In the current study, we observed that the long non-coding RNA (lncRNA) MIAT was notice...

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Bibliographic Details
Main Authors: Ziyang Wang, Ying Chang, Yue Liu, Bing Liu, Junhui Zhen, Xiaobing Li, Jiangong Lin, Qun Yu, Zhimei Lv, Rong Wang
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT
diabetic nephropathy
MIAT
podocyte
mitotic catastrophe
Sox4
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253122000506

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