Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association

Antiphospholipid syndrome (APS) is an autoimmune disease that manifests as recurrent venous or arterial thrombosis and/or pregnancy-related complications in the presence of persistent antiphospholipid (aPL) antibodies measured at least 3 months apart. APS occurs either as a primary condition or as a...

Full description

Bibliographic Details
Main Author: Mathilde Versini
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00175/full
_version_ 1819182991959654400
author Mathilde Versini
author_facet Mathilde Versini
author_sort Mathilde Versini
collection DOAJ
description Antiphospholipid syndrome (APS) is an autoimmune disease that manifests as recurrent venous or arterial thrombosis and/or pregnancy-related complications in the presence of persistent antiphospholipid (aPL) antibodies measured at least 3 months apart. APS occurs either as a primary condition or as a part of an underlying disorder, usually systemic lupus erythematosus (SLE). Otherwise, APS may be frequently associated with autoimmune disorders. Little is known about the association of APS and aPL antibodies with thyroid autoimmune diseases or thyroid autoantibodies. This is even more interesting that thyroid autoantibodies and aPL are both recognized causes of repeated miscarriages. Therefore, their combination is of particular importance in women of childbearing age. Several studies have pointed out an association between APS and thyroid autoimmunity, some of them suggesting common pathophysiologic processes and genetic background. A literature review was conducted on existing data on aPL/APS and thyroid autoimmune disorders, paying particular attention to the possible role of this association in obstetrical complications.
first_indexed 2024-12-22T22:54:56Z
format Article
id doaj.art-ac9ae9664b1044ee97fc790a8b90629e
institution Directory Open Access Journal
issn 1664-2392
language English
last_indexed 2024-12-22T22:54:56Z
publishDate 2017-07-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Endocrinology
spelling doaj.art-ac9ae9664b1044ee97fc790a8b90629e2022-12-21T18:09:51ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922017-07-01810.3389/fendo.2017.00175277201Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial AssociationMathilde Versini0Department of Internal Medicine, Archet-1 Hospital, University Hospital of Nice, Nice, FranceAntiphospholipid syndrome (APS) is an autoimmune disease that manifests as recurrent venous or arterial thrombosis and/or pregnancy-related complications in the presence of persistent antiphospholipid (aPL) antibodies measured at least 3 months apart. APS occurs either as a primary condition or as a part of an underlying disorder, usually systemic lupus erythematosus (SLE). Otherwise, APS may be frequently associated with autoimmune disorders. Little is known about the association of APS and aPL antibodies with thyroid autoimmune diseases or thyroid autoantibodies. This is even more interesting that thyroid autoantibodies and aPL are both recognized causes of repeated miscarriages. Therefore, their combination is of particular importance in women of childbearing age. Several studies have pointed out an association between APS and thyroid autoimmunity, some of them suggesting common pathophysiologic processes and genetic background. A literature review was conducted on existing data on aPL/APS and thyroid autoimmune disorders, paying particular attention to the possible role of this association in obstetrical complications.http://journal.frontiersin.org/article/10.3389/fendo.2017.00175/fullantiphospholipid syndromeautoimmunitythyroidHashimoto’s thyroiditisGraves’ diseaseautoimmune disease
spellingShingle Mathilde Versini
Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
Frontiers in Endocrinology
antiphospholipid syndrome
autoimmunity
thyroid
Hashimoto’s thyroiditis
Graves’ disease
autoimmune disease
title Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
title_full Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
title_fullStr Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
title_full_unstemmed Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
title_short Thyroid Autoimmunity and Antiphospholipid Syndrome: Not Such a Trivial Association
title_sort thyroid autoimmunity and antiphospholipid syndrome not such a trivial association
topic antiphospholipid syndrome
autoimmunity
thyroid
Hashimoto’s thyroiditis
Graves’ disease
autoimmune disease
url http://journal.frontiersin.org/article/10.3389/fendo.2017.00175/full
work_keys_str_mv AT mathildeversini thyroidautoimmunityandantiphospholipidsyndromenotsuchatrivialassociation