Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.

Vinculin association with actin cytoskeleton is necessary for stiffness-dependent regulation of vinculin behavior.

The extracellular matrix (ECM) is a major regulator of cell behavior. Recent studies have indicated the importance of the physical properties of the ECM, including its stiffness, for cell migration and differentiation. Using actomyosin-generated forces, cells pull the ECM and sense stiffness via cel...

Full description

Bibliographic Details
Main Authors: Tomohiro Omachi, Takafumi Ichikawa, Yasuhisa Kimura, Kazumitsu Ueda, Noriyuki Kioka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5384775?pdf=render

Similar Items

Similar Items