Genomic selection for carrier-state resistance in chicken commercial lines
<p>Abstract</p> <p>Background</p> <p><it>Salmonella</it> propagation by apparently healthy chicken and subsequent food security concerns could be decreased by the selection and use of chicken lines more resistant to carrier-state. In the present study we app...
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| Format: | Article |
| Language: | English |
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BMC
2011-06-01
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| Series: | BMC Proceedings |
| _version_ | 1811298502990364672 |
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| author | Calenge Fanny Legarra Andres Beaumont Catherine |
| author_facet | Calenge Fanny Legarra Andres Beaumont Catherine |
| author_sort | Calenge Fanny |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p><it>Salmonella</it> propagation by apparently healthy chicken and subsequent food security concerns could be decreased by the selection and use of chicken lines more resistant to carrier-state. In the present study we applied the first steps of the genomic selection methodology to assess the interest of including genetic markers for the genetic evaluation of hen lines infected with <it>Salmonella Enteritidis</it>.</p> <p>Methods</p> <p>We studied commercial laying hen lines divergently selected for resistance to <it>Salmonella</it> carrier-state at two different ages. A total of 600 animals were typed with 1536 SNP markers and artificially infected with <it>S.</it> Enteritidis. Phenotypes were collected four weeks (young animals) or five weeks (adults) later. Two types of variance component analyses, including or not including SNP data, were performed and compared. All variance components were estimated by Bayesian methods and Gibbs sampling.</p> <p>Results</p> <p>The comparison of both genetic analyses shows that SNP are efficient in capturing genetic variation, although none of them captures a large affect on the traits studied. Average accuracies do not change between analyses, showing that using SNP data does not really increase information.</p> <p>Conclusions</p> <p>These preliminary results show that genomic selection for <it>Salmonella</it> carrier-state resistance in laying hens is promising, although a denser SNP coverage of the genome on a higher number of animals is needed to assess its feasibility and efficiency compared to classical pedigree evaluation.</p> |
| first_indexed | 2024-04-13T06:20:15Z |
| format | Article |
| id | doaj.art-ac9dc34dc1354e60bbc6921c885f6b82 |
| institution | Directory Open Access Journal |
| issn | 1753-6561 |
| language | English |
| last_indexed | 2024-04-13T06:20:15Z |
| publishDate | 2011-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Proceedings |
| spelling | doaj.art-ac9dc34dc1354e60bbc6921c885f6b822022-12-22T02:58:40ZengBMCBMC Proceedings1753-65612011-06-015Suppl 4S2410.1186/1753-6561-5-S4-S24Genomic selection for carrier-state resistance in chicken commercial linesCalenge FannyLegarra AndresBeaumont Catherine<p>Abstract</p> <p>Background</p> <p><it>Salmonella</it> propagation by apparently healthy chicken and subsequent food security concerns could be decreased by the selection and use of chicken lines more resistant to carrier-state. In the present study we applied the first steps of the genomic selection methodology to assess the interest of including genetic markers for the genetic evaluation of hen lines infected with <it>Salmonella Enteritidis</it>.</p> <p>Methods</p> <p>We studied commercial laying hen lines divergently selected for resistance to <it>Salmonella</it> carrier-state at two different ages. A total of 600 animals were typed with 1536 SNP markers and artificially infected with <it>S.</it> Enteritidis. Phenotypes were collected four weeks (young animals) or five weeks (adults) later. Two types of variance component analyses, including or not including SNP data, were performed and compared. All variance components were estimated by Bayesian methods and Gibbs sampling.</p> <p>Results</p> <p>The comparison of both genetic analyses shows that SNP are efficient in capturing genetic variation, although none of them captures a large affect on the traits studied. Average accuracies do not change between analyses, showing that using SNP data does not really increase information.</p> <p>Conclusions</p> <p>These preliminary results show that genomic selection for <it>Salmonella</it> carrier-state resistance in laying hens is promising, although a denser SNP coverage of the genome on a higher number of animals is needed to assess its feasibility and efficiency compared to classical pedigree evaluation.</p> |
| spellingShingle | Calenge Fanny Legarra Andres Beaumont Catherine Genomic selection for carrier-state resistance in chicken commercial lines BMC Proceedings |
| title | Genomic selection for carrier-state resistance in chicken commercial lines |
| title_full | Genomic selection for carrier-state resistance in chicken commercial lines |
| title_fullStr | Genomic selection for carrier-state resistance in chicken commercial lines |
| title_full_unstemmed | Genomic selection for carrier-state resistance in chicken commercial lines |
| title_short | Genomic selection for carrier-state resistance in chicken commercial lines |
| title_sort | genomic selection for carrier state resistance in chicken commercial lines |
| work_keys_str_mv | AT calengefanny genomicselectionforcarrierstateresistanceinchickencommerciallines AT legarraandres genomicselectionforcarrierstateresistanceinchickencommerciallines AT beaumontcatherine genomicselectionforcarrierstateresistanceinchickencommerciallines |