Prenatal features of congenital peribronchial myofibroblastic tumor
Here, we report a case of a congenital peribronchial myofibroblastic tumor (CPMT). A 34-year-old primigravida was referred to our hospital at 31 gestation weeks because of suspected congenital pulmonary airway malformation (CPAM). Fetal ultrasonography showed a mass measuring 4.6 × 4.0 × 3.9 cm with...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-04-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324000025 |
| _version_ | 1797292982546726912 |
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| author | Hitoshi Isohata Tsutomu Yoshida Itaru Sanoyama Yu Yamazaki Hiroyuki Goto Yoshihiro Yoshimura Kyoko Hattori Takao Shimaoka Kazuki Sekiguchi Yoko Onishi Kiyoshi Tanaka Daigo Ochiai |
| author_facet | Hitoshi Isohata Tsutomu Yoshida Itaru Sanoyama Yu Yamazaki Hiroyuki Goto Yoshihiro Yoshimura Kyoko Hattori Takao Shimaoka Kazuki Sekiguchi Yoko Onishi Kiyoshi Tanaka Daigo Ochiai |
| author_sort | Hitoshi Isohata |
| collection | DOAJ |
| description | Here, we report a case of a congenital peribronchial myofibroblastic tumor (CPMT). A 34-year-old primigravida was referred to our hospital at 31 gestation weeks because of suspected congenital pulmonary airway malformation (CPAM). Fetal ultrasonography showed a mass measuring 4.6 × 4.0 × 3.9 cm with mixed high and low echogenicity in the left lung, which was associated with microvascular blood flow in the tumor. Fetal magnetic resonance imaging (MRI) revealed a low-intensity left lobe lung lesion on a T2-weighted image. These findings suggested that the mass was a CPAM with atypical hypointense findings on MRI T2-weighted images or a rare primary pulmonary tumor, such as a CPMT. Unfortunately, the fetus died in utero at 34 gestation weeks due to cardiovascular failure, which could have resulted from direct encasement of the great vessels or cardiac compression due to rapid tumor growth. The autopsy findings confirmed the diagnosis of CPMT. Primary pulmonary tumors, such as CPMT, are extremely rare lung diseases that develop in utero. These tumors often rapidly grow during pregnancy, resulting in intrauterine fetal death. However, if the patient survives surgical mass resection, the prognosis is good. Given the adverse outcomes observed in our case, careful fetal monitoring is required in case of suspected CPMT during the third trimester of pregnancy. Moreover, in case the well-being of the fetus cannot be assured, immediate delivery should be considered, even in the preterm period, followed by surgery. |
| first_indexed | 2024-03-07T20:05:20Z |
| format | Article |
| id | doaj.art-ac9e8ddad8b748f3b98ec2719797c639 |
| institution | Directory Open Access Journal |
| issn | 1930-0433 |
| language | English |
| last_indexed | 2024-03-07T20:05:20Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj.art-ac9e8ddad8b748f3b98ec2719797c6392024-02-28T05:13:05ZengElsevierRadiology Case Reports1930-04332024-04-0119414631467Prenatal features of congenital peribronchial myofibroblastic tumorHitoshi Isohata0Tsutomu Yoshida1Itaru Sanoyama2Yu Yamazaki3Hiroyuki Goto4Yoshihiro Yoshimura5Kyoko Hattori6Takao Shimaoka7Kazuki Sekiguchi8Yoko Onishi9Kiyoshi Tanaka10Daigo Ochiai11Department of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDivision of Molecular Pathology, Department of Comprehensive Medicine, Research and Development Center for New Medical Frontiers, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Pathology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Pediatric Surgery, Kitasato University School of Medicine, Sagamihara, JapanDepartment of Obstetrics and Gynecology, Kitasato University School of Medicine, Sagamihara, Japan; Corresponding author.Here, we report a case of a congenital peribronchial myofibroblastic tumor (CPMT). A 34-year-old primigravida was referred to our hospital at 31 gestation weeks because of suspected congenital pulmonary airway malformation (CPAM). Fetal ultrasonography showed a mass measuring 4.6 × 4.0 × 3.9 cm with mixed high and low echogenicity in the left lung, which was associated with microvascular blood flow in the tumor. Fetal magnetic resonance imaging (MRI) revealed a low-intensity left lobe lung lesion on a T2-weighted image. These findings suggested that the mass was a CPAM with atypical hypointense findings on MRI T2-weighted images or a rare primary pulmonary tumor, such as a CPMT. Unfortunately, the fetus died in utero at 34 gestation weeks due to cardiovascular failure, which could have resulted from direct encasement of the great vessels or cardiac compression due to rapid tumor growth. The autopsy findings confirmed the diagnosis of CPMT. Primary pulmonary tumors, such as CPMT, are extremely rare lung diseases that develop in utero. These tumors often rapidly grow during pregnancy, resulting in intrauterine fetal death. However, if the patient survives surgical mass resection, the prognosis is good. Given the adverse outcomes observed in our case, careful fetal monitoring is required in case of suspected CPMT during the third trimester of pregnancy. Moreover, in case the well-being of the fetus cannot be assured, immediate delivery should be considered, even in the preterm period, followed by surgery.http://www.sciencedirect.com/science/article/pii/S1930043324000025Congenital peribronchial myofibroblastic tumorPrenatal diagnosisFetal MRIUltrasound |
| spellingShingle | Hitoshi Isohata Tsutomu Yoshida Itaru Sanoyama Yu Yamazaki Hiroyuki Goto Yoshihiro Yoshimura Kyoko Hattori Takao Shimaoka Kazuki Sekiguchi Yoko Onishi Kiyoshi Tanaka Daigo Ochiai Prenatal features of congenital peribronchial myofibroblastic tumor Radiology Case Reports Congenital peribronchial myofibroblastic tumor Prenatal diagnosis Fetal MRI Ultrasound |
| title | Prenatal features of congenital peribronchial myofibroblastic tumor |
| title_full | Prenatal features of congenital peribronchial myofibroblastic tumor |
| title_fullStr | Prenatal features of congenital peribronchial myofibroblastic tumor |
| title_full_unstemmed | Prenatal features of congenital peribronchial myofibroblastic tumor |
| title_short | Prenatal features of congenital peribronchial myofibroblastic tumor |
| title_sort | prenatal features of congenital peribronchial myofibroblastic tumor |
| topic | Congenital peribronchial myofibroblastic tumor Prenatal diagnosis Fetal MRI Ultrasound |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324000025 |
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