Molecular Targeting of VEGF with a Suramin Fragment–DOCA Conjugate by Mimicking the Action of Low Molecular Weight Heparins

Molecular Targeting of VEGF with a Suramin Fragment–DOCA Conjugate by Mimicking the Action of Low Molecular Weight Heparins

Molecular targeting of growth factors has shown great therapeutic potential in pharmaceutical research due to their roles in pathological conditions. In the present study, we developed a novel suramin fragment and deoxycholic acid conjugate (SFD) that exhibited the potential to bind to the heparin-b...

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Bibliographic Details
Main Authors: Jooho Park, Tae-Bong Kang, Ji-Hong Lim, Hyung-Sik Won
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biomolecules
Subjects:
VEGF
molecular targeting
drug development
suramin
heparin
Online Access:https://www.mdpi.com/2218-273X/11/1/46

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