Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey
OBJECTIVES: Estimate the prevalence of immunity to poliomyelitis (anti-polio antibodies) in the city of São Paulo/Brazil through a population-based survey. METHODS: A quantitative and inductive method was used to draw a representative sample of the population. Randomization and stratification (based...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2002-01-01
|
| Series: | Brazilian Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000500004 |
| _version_ | 1819289432896831488 |
|---|---|
| author | Kiffer Carlos Roberto Veiga Conceição Orlando Jorge Santos Edgar Bortholi Sabino Ester Focaccia Roberto |
| author_facet | Kiffer Carlos Roberto Veiga Conceição Orlando Jorge Santos Edgar Bortholi Sabino Ester Focaccia Roberto |
| author_sort | Kiffer Carlos Roberto Veiga |
| collection | DOAJ |
| description | OBJECTIVES: Estimate the prevalence of immunity to poliomyelitis (anti-polio antibodies) in the city of São Paulo/Brazil through a population-based survey. METHODS: A quantitative and inductive method was used to draw a representative sample of the population. Randomization and stratification (based on sex, age and residence region) was done, and 1,059 individuals were studied on a home-visit basis (structured questionnaires and blood samples). A microneutralization test was performed to detect anti-polio antibodies against serotypes 1, 2 and 3. RESULTS: The estimated prevalence of immunity to poliomyelitis was high, with 94.6% prevalence of anti-polio 1 antibodies, 98.8% anti-polio 2 and 91.9% anti-polio 3. Despite this high prevalence, there were significantly lower prevalence levels in some groups, specially among age and residence region groups. DISCUSSION: Routine child immunization and NIDs with OPV have provided excellent levels of serological immunity to poliomyelitis in the population of the city of São Paulo, Brazil. However, there may be specific groups with a lower prevalence of immunity. Estimations of the prevalence of immunity to poliomyelitis were made in a population-based survey, which could be used as an auxiliary tool for supporting the polio eradication program. |
| first_indexed | 2024-12-24T03:06:46Z |
| format | Article |
| id | doaj.art-ac9fafaf13404e499f3963eb9815af00 |
| institution | Directory Open Access Journal |
| issn | 1413-8670 1678-4391 |
| language | English |
| last_indexed | 2024-12-24T03:06:46Z |
| publishDate | 2002-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brazilian Journal of Infectious Diseases |
| spelling | doaj.art-ac9fafaf13404e499f3963eb9815af002022-12-21T17:17:59ZengElsevierBrazilian Journal of Infectious Diseases1413-86701678-43912002-01-0165232243Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based surveyKiffer Carlos Roberto VeigaConceição Orlando JorgeSantos Edgar BortholiSabino EsterFocaccia RobertoOBJECTIVES: Estimate the prevalence of immunity to poliomyelitis (anti-polio antibodies) in the city of São Paulo/Brazil through a population-based survey. METHODS: A quantitative and inductive method was used to draw a representative sample of the population. Randomization and stratification (based on sex, age and residence region) was done, and 1,059 individuals were studied on a home-visit basis (structured questionnaires and blood samples). A microneutralization test was performed to detect anti-polio antibodies against serotypes 1, 2 and 3. RESULTS: The estimated prevalence of immunity to poliomyelitis was high, with 94.6% prevalence of anti-polio 1 antibodies, 98.8% anti-polio 2 and 91.9% anti-polio 3. Despite this high prevalence, there were significantly lower prevalence levels in some groups, specially among age and residence region groups. DISCUSSION: Routine child immunization and NIDs with OPV have provided excellent levels of serological immunity to poliomyelitis in the population of the city of São Paulo, Brazil. However, there may be specific groups with a lower prevalence of immunity. Estimations of the prevalence of immunity to poliomyelitis were made in a population-based survey, which could be used as an auxiliary tool for supporting the polio eradication program.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000500004Immunity prevalencepoliomyelitispolivirusesseroepidemiologic studiesantibodiesviral blood |
| spellingShingle | Kiffer Carlos Roberto Veiga Conceição Orlando Jorge Santos Edgar Bortholi Sabino Ester Focaccia Roberto Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey Brazilian Journal of Infectious Diseases Immunity prevalence poliomyelitis poliviruses seroepidemiologic studies antibodies viral blood |
| title | Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey |
| title_full | Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey |
| title_fullStr | Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey |
| title_full_unstemmed | Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey |
| title_short | Estimated prevalence of immunity to poliomyelitis in the city of São Paulo, Brazil: a population-based survey |
| title_sort | estimated prevalence of immunity to poliomyelitis in the city of sao paulo brazil a population based survey |
| topic | Immunity prevalence poliomyelitis poliviruses seroepidemiologic studies antibodies viral blood |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702002000500004 |
| work_keys_str_mv | AT kiffercarlosrobertoveiga estimatedprevalenceofimmunitytopoliomyelitisinthecityofsaopaulobrazilapopulationbasedsurvey AT conceicaoorlandojorge estimatedprevalenceofimmunitytopoliomyelitisinthecityofsaopaulobrazilapopulationbasedsurvey AT santosedgarbortholi estimatedprevalenceofimmunitytopoliomyelitisinthecityofsaopaulobrazilapopulationbasedsurvey AT sabinoester estimatedprevalenceofimmunitytopoliomyelitisinthecityofsaopaulobrazilapopulationbasedsurvey AT focacciaroberto estimatedprevalenceofimmunitytopoliomyelitisinthecityofsaopaulobrazilapopulationbasedsurvey |