LMP1-induced cell death may contribute to the emergency of its oncogenic property.

LMP1-induced cell death may contribute to the emergency of its oncogenic property.

BACKGROUND AND OBJECTIVES: Epstein-Barr Virus (EBV) Latent Membrane Protein 1 (LMP1) is linked to a variety of malignancies including Hodgkin's disease, lymphomas, nasopharyngeal and gastric carcinoma. LMP1 exerts its transforming or oncogenic activity mainly through the recruitment of intracel...

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Main Authors: Guillaume Brocqueville, Papa Alioune Ndour, Tan-Sothéa Ouk, Arnaud Le Goff, Caroline De Witte, Alexandra Mougel, Jean Coll, Véronique Fafeur, Xuefen Le Bourhis, Eric Adriaenssens
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3634045?pdf=render

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