Deletion of the primase-polymerases encoding gene, located in a mobile element in Thermus thermophilus HB27, leads to loss of function mutation of addAB genes

Deletion of the primase-polymerases encoding gene, located in a mobile element in Thermus thermophilus HB27, leads to loss of function mutation of addAB genes

DNA primase-polymerases (Ppol) have been shown to play active roles in DNA repair and damage tolerance, both in prokaryotes and eukaryotes. The ancestral thermophilic bacterium Thermus thermophilus strain HB27 encodes a Ppol protein among the genes present in mobile element ICETh2, absent in other T...

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Bibliographic Details
Main Authors: Carlos Verdú, Patricia Pérez-Arnaiz, Ana Peropadre, José Berenguer, Mario Mencía
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
PrimPol
Thermus thermophilus
AddAB
comet assay
bacterial transformation
DNA repair
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1005862/full

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