From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma
Respiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We r...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
|
| Series: | Children |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2227-9067/9/9/1361 |
| _version_ | 1797489953076150272 |
|---|---|
| author | Joanna Maria Jassem-Bobowicz Ewa Magdalena Sokołowska Katarzyna Monika Hinca Izabela Drążkowska Katarzyna Stefańska |
| author_facet | Joanna Maria Jassem-Bobowicz Ewa Magdalena Sokołowska Katarzyna Monika Hinca Izabela Drążkowska Katarzyna Stefańska |
| author_sort | Joanna Maria Jassem-Bobowicz |
| collection | DOAJ |
| description | Respiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We report on a male neonate born at 36 + 4/7 weeks of gestation, diagnosed with retropharyngeal synovial carcinoma. Ineffective respiratory movements and generalized cyanosis were the first symptoms to be noted. On the ultrasound examination of the neck, a tumor of the retropharyngeal space was exposed, then visualized by an MRI of the head and neck. The biopsy analysis revealed the diagnosis of an extremely rare tumor in a neonate. The location of its growth was atypical, contributing to a diagnostic challenge. The neoplasm was treated solely with chemotherapy concordantly with the CWS protocol, individually customized for our patient. Preterm birth, as in our case, 36 + 4/7 weeks of gestation, may imply a possible need for resuscitation or support in the transition period. Aggressive high-grade tumors of the head and neck region are locally invasive and prone to metastasize. However, prognosis in infants is hard to estimate, therefore both individualized treatment and multidisciplinary care should be tailored to the needs of the patient. |
| first_indexed | 2024-03-10T00:24:01Z |
| format | Article |
| id | doaj.art-aca5bbf3a88548bcb5d5f6ea069b9aea |
| institution | Directory Open Access Journal |
| issn | 2227-9067 |
| language | English |
| last_indexed | 2024-03-10T00:24:01Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj.art-aca5bbf3a88548bcb5d5f6ea069b9aea2023-11-23T15:37:47ZengMDPI AGChildren2227-90672022-09-0199136110.3390/children9091361From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell CarcinomaJoanna Maria Jassem-Bobowicz0Ewa Magdalena Sokołowska1Katarzyna Monika Hinca2Izabela Drążkowska3Katarzyna Stefańska4Division of Neonatology, Medical University of Gdańsk, 80-210 Gdańsk, PolandScientific Students’ Circle, Division of Neonatology, Medical University of Gdańsk, 80-210 Gdańsk, PolandDivision of Neonatology, Medical University of Gdańsk, 80-210 Gdańsk, PolandDivision of Neonatology, Medical University of Gdańsk, 80-210 Gdańsk, PolandDivision of Gynecology and Obstetrics, Medical University of Gdańsk, 80-210 Gdańsk, PolandRespiratory complications are among the most common problems addressed in neonatology in the first hours after birth, whereas the risk of any cancer in the neonatal period is 28 per million. Sarcomas, malignant mesenchymal neoplasms, account for about 8% of all neoplasms in the neonatal period. We report on a male neonate born at 36 + 4/7 weeks of gestation, diagnosed with retropharyngeal synovial carcinoma. Ineffective respiratory movements and generalized cyanosis were the first symptoms to be noted. On the ultrasound examination of the neck, a tumor of the retropharyngeal space was exposed, then visualized by an MRI of the head and neck. The biopsy analysis revealed the diagnosis of an extremely rare tumor in a neonate. The location of its growth was atypical, contributing to a diagnostic challenge. The neoplasm was treated solely with chemotherapy concordantly with the CWS protocol, individually customized for our patient. Preterm birth, as in our case, 36 + 4/7 weeks of gestation, may imply a possible need for resuscitation or support in the transition period. Aggressive high-grade tumors of the head and neck region are locally invasive and prone to metastasize. However, prognosis in infants is hard to estimate, therefore both individualized treatment and multidisciplinary care should be tailored to the needs of the patient.https://www.mdpi.com/2227-9067/9/9/1361newbornpolyhydramniosairway patencyrespiratory insufficiencyneonatal resuscitationbiphasic synovial sarcoma |
| spellingShingle | Joanna Maria Jassem-Bobowicz Ewa Magdalena Sokołowska Katarzyna Monika Hinca Izabela Drążkowska Katarzyna Stefańska From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma Children newborn polyhydramnios airway patency respiratory insufficiency neonatal resuscitation biphasic synovial sarcoma |
| title | From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma |
| title_full | From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma |
| title_fullStr | From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma |
| title_full_unstemmed | From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma |
| title_short | From the Difficult Airway Management to Diagnosis of Retropharyngeal Synovial Cell Carcinoma |
| title_sort | from the difficult airway management to diagnosis of retropharyngeal synovial cell carcinoma |
| topic | newborn polyhydramnios airway patency respiratory insufficiency neonatal resuscitation biphasic synovial sarcoma |
| url | https://www.mdpi.com/2227-9067/9/9/1361 |
| work_keys_str_mv | AT joannamariajassembobowicz fromthedifficultairwaymanagementtodiagnosisofretropharyngealsynovialcellcarcinoma AT ewamagdalenasokołowska fromthedifficultairwaymanagementtodiagnosisofretropharyngealsynovialcellcarcinoma AT katarzynamonikahinca fromthedifficultairwaymanagementtodiagnosisofretropharyngealsynovialcellcarcinoma AT izabeladrazkowska fromthedifficultairwaymanagementtodiagnosisofretropharyngealsynovialcellcarcinoma AT katarzynastefanska fromthedifficultairwaymanagementtodiagnosisofretropharyngealsynovialcellcarcinoma |