Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction
Objective The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score). Methods A prospective, observational, non-inter...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2024-01-01
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| Series: | ERJ Open Research |
| Online Access: | http://openres.ersjournals.com/content/10/1/00488-2023.full |
| _version_ | 1797278856844935168 |
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| author | Cristóbal Esteban Nere Aguirre Amaia Aramburu Javier Moraza Leyre Chasco Myriam Aburto Susana Aizpiri Rafael Golpe José M. Quintana |
| author_facet | Cristóbal Esteban Nere Aguirre Amaia Aramburu Javier Moraza Leyre Chasco Myriam Aburto Susana Aizpiri Rafael Golpe José M. Quintana |
| author_sort | Cristóbal Esteban |
| collection | DOAJ |
| description | Objective
The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score).
Methods
A prospective, observational, non-intervention study was carried out. Patients were recruited from the six outpatient clinics of the respiratory service of a single university hospital. The component variables of the HADO.2 score and BODE index were studied, and PA was measured using an accelerometer. The outcomes for the HADO.2 score were mortality and hospitalisations during follow-up and an exploration of the correlation with health-related quality of life at the moment of inclusion in the study.
Results
401 patients were included in the study and followed up for three years. The HADO.2 score showed good predictive capacity for mortality: C-index 0.79 (0.72–0.85). The C-index for hospitalisations was 0.72 (0.66–0.77) and the predictive ability for quality of life, as measured by R2, was 0.63 and 0.53 respectively for the Saint George's Respiratory Questionnaire and COPD Assessment Test.
Conclusions
There was no statistically significant difference between the mortality predictive capacity of the HADO.2 score and the BODE index. Adding PA to the original BODE index significantly improved the predictive capacity of the index. The HADO.2 score, which includes PA as a key variable, showed good predictive capacity for mortality and hospitalisations. There were no differences in the predictive capacity of the HADO.2 score and the BODE index. |
| first_indexed | 2024-03-07T16:15:09Z |
| format | Article |
| id | doaj.art-aca8788565584ed6abf9d2959a401182 |
| institution | Directory Open Access Journal |
| issn | 2312-0541 |
| language | English |
| last_indexed | 2024-03-07T16:15:09Z |
| publishDate | 2024-01-01 |
| publisher | European Respiratory Society |
| record_format | Article |
| series | ERJ Open Research |
| spelling | doaj.art-aca8788565584ed6abf9d2959a4011822024-03-04T11:29:59ZengEuropean Respiratory SocietyERJ Open Research2312-05412024-01-0110110.1183/23120541.00488-202300488-2023Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstructionCristóbal Esteban0Nere Aguirre1Amaia Aramburu2Javier Moraza3Leyre Chasco4Myriam Aburto5Susana Aizpiri6Rafael Golpe7José M. Quintana8 Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Kronikgune Research Institute, Baracaldo, Spain Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Respiratory Department, Hospital Universitario Galdakao-Usansolo, Galdakao, Spain Respiratory Department, Hospital Universitario Lucus Augusti, Lugo, Spain Health Services Research on Chronic Patients Network (REDISSEC), Galdakao, Spain Objective The aim of this study was to create a prognostic instrument for COPD with a multidimensional perspective that includes physical activity (PA). The score also included health status, dyspnoea and forced expiratory volume in 1 s (HADO.2 score). Methods A prospective, observational, non-intervention study was carried out. Patients were recruited from the six outpatient clinics of the respiratory service of a single university hospital. The component variables of the HADO.2 score and BODE index were studied, and PA was measured using an accelerometer. The outcomes for the HADO.2 score were mortality and hospitalisations during follow-up and an exploration of the correlation with health-related quality of life at the moment of inclusion in the study. Results 401 patients were included in the study and followed up for three years. The HADO.2 score showed good predictive capacity for mortality: C-index 0.79 (0.72–0.85). The C-index for hospitalisations was 0.72 (0.66–0.77) and the predictive ability for quality of life, as measured by R2, was 0.63 and 0.53 respectively for the Saint George's Respiratory Questionnaire and COPD Assessment Test. Conclusions There was no statistically significant difference between the mortality predictive capacity of the HADO.2 score and the BODE index. Adding PA to the original BODE index significantly improved the predictive capacity of the index. The HADO.2 score, which includes PA as a key variable, showed good predictive capacity for mortality and hospitalisations. There were no differences in the predictive capacity of the HADO.2 score and the BODE index.http://openres.ersjournals.com/content/10/1/00488-2023.full |
| spellingShingle | Cristóbal Esteban Nere Aguirre Amaia Aramburu Javier Moraza Leyre Chasco Myriam Aburto Susana Aizpiri Rafael Golpe José M. Quintana Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction ERJ Open Research |
| title | Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction |
| title_full | Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction |
| title_fullStr | Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction |
| title_full_unstemmed | Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction |
| title_short | Influence of physical activity on the prognosis of COPD patients: the HADO.2 score – health, activity, dyspnoea and obstruction |
| title_sort | influence of physical activity on the prognosis of copd patients the hado 2 score health activity dyspnoea and obstruction |
| url | http://openres.ersjournals.com/content/10/1/00488-2023.full |
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