microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney

microRNA Crosstalk Influences Epithelial-to-Mesenchymal, Endothelial-to-Mesenchymal, and Macrophage-to-Mesenchymal Transitions in the Kidney

microRNAs (miRNAs) are small, non-coding nucleotides that regulate diverse biological processes. Altered microRNA biosynthesis or regulation contributes to pathological processes including kidney fibrosis. Kidney fibrosis is characterized by deposition of excess extracellular matrix (ECM), which is...

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Bibliographic Details
Main Authors: Swayam Prakash Srivastava, Ahmad F. Hedayat, Keizo Kanasaki, Julie E. Goodwin
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Pharmacology
Subjects:
microRNAs
diabetic kidney disease
kidney fibrosis
microRNA crosstalk
epithelial-to-mesenchymal transition
endothelial-to-mesenchymal transition
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2019.00904/full

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