Response of estrogen receptor-positive breast cancer tumorspheres to antiestrogen treatments.

Response of estrogen receptor-positive breast cancer tumorspheres to antiestrogen treatments.

Estrogen signaling plays a critical role in the pathogenesis of breast cancer. Because the majority of breast carcinomas express the estrogen receptor ERα, endocrine therapy that impedes estrogen-ER signaling reduces breast cancer mortality and has become a mainstay of breast cancer treatment. Howev...

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Bibliographic Details
Main Authors: Ada Ao, Brian J Morrison, Heiman Wang, J Alejandro López, Brent A Reynolds, Jianrong Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3077404?pdf=render

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