Assessment of Changes in Birefringence and Orientation of Collagen Fibres in Different Grades of Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma using Picrosirius Red and Polarising Microscopy

Assessment of Changes in Birefringence and Orientation of Collagen Fibres in Different Grades of Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma using Picrosirius Red and Polarising Microscopy

Introduction: Oral Submucous Fibrosis (OSMF) is a potentially malignant disease with a prevalence of 7-13%. It is characterised by the fibroelastic changes due to excessive deposition of collagen which results in dense fibrous bands and epithelial changes. About 90-95% of oral cancers are Oral Squam...

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Bibliographic Details
Main Authors: Ashwini Chikkanayakanahalli Prabhakar, HC Girish, Varsha Vimal Kumar, Umapathy Thimmegowda, Praveen Mallavalli Nagaraj Shetty
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2022-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
extracellular matrix
fibroelastic changes
malignancy orientation
Online Access:https://jcdr.net/articles/PDF/16721/53504_CE[Nik]_F_(KR)_PF1(PS_SHU_SS)_PFA(PS_KM)_PN(KM).pdf

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