Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study
Abstract Background Radical or conservative surgical treatment for hepatic Cystic Echinococcosis (hepatic CE) is controversial. We aimed to measure the association between radical surgery (RS) versus conservative surgery (CS) and short-term outcomes in our cohort. Methods Medical records of hepatic...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-05-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-023-02000-y |
| _version_ | 1797827727952183296 |
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| author | Liangping Huang Benrong Zheng Aduo Ouzhulamu Xi Li Jianchun Yao |
| author_facet | Liangping Huang Benrong Zheng Aduo Ouzhulamu Xi Li Jianchun Yao |
| author_sort | Liangping Huang |
| collection | DOAJ |
| description | Abstract Background Radical or conservative surgical treatment for hepatic Cystic Echinococcosis (hepatic CE) is controversial. We aimed to measure the association between radical surgery (RS) versus conservative surgery (CS) and short-term outcomes in our cohort. Methods Medical records of hepatic CE patients’ demographic, clinical, radiological, operative and postoperative details who underwent surgical treatment between January 3, 2017 and January 3, 2018 at the Department of General Surgery, Nyingchi People's Hospital, Nyingchi, China, were retrieved and analyzed. The primary outcome was overall morbidity. The secondary outcomes included: (i) bile leakage; (ii) complications of lung, pleura, heart, liver, pancreas and biliary tract; (iii) incision infection and residual cavity abscess formation; (iv) anaphylactic reaction and shock; (v) tear of surrounding tissues; (vi) hospital and post-operative length of stay (LOS); (vii) length of surgery; (viii) blood loss during surgery. Multivariable logistic/linear regression models with various adjustment strategies for confounders were performed to evaluate the association. Results A total of 128 hepatic CE patients were included with 82 (64.1%) and 46 (35.9%) receiving CS and RS, respectively. After fully adjusted, RS was associated with 60% lower risk of overall complication (aOR 0.4; 95%CI, 0.2–0.9) and 0.6-h shorter surgical time (aβ 0.4; 95%CI,-0.0–0.8) comparing to CS. However, RS was associated with more blood loss during surgery (aβ 179.3; 95%CI, 54.2–304.5). Conclusion To conclude, RS was associated with a 60% reduction in developing overall complication in the short term, but may result in more blood loss during surgery than CS. |
| first_indexed | 2024-04-09T12:53:00Z |
| format | Article |
| id | doaj.art-acae3692e8f74248b1717880fd9bb798 |
| institution | Directory Open Access Journal |
| issn | 1471-2482 |
| language | English |
| last_indexed | 2024-04-09T12:53:00Z |
| publishDate | 2023-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj.art-acae3692e8f74248b1717880fd9bb7982023-05-14T11:06:59ZengBMCBMC Surgery1471-24822023-05-012311810.1186/s12893-023-02000-yAssociation between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort studyLiangping Huang0Benrong Zheng1Aduo2Ouzhulamu3Xi Li4Jianchun Yao5Department of Drug and Medical Device Clinical Trial Office, The Second Affiliated Hospital of Shantou University Medical CollegePhysical Examination Center, Nyingchi People’s HospitalDepartment of General Surgery, Nyingchi People’s HospitalDepartment of General Surgery, Nyingchi People’s HospitalDepartment of General Surgery, Nyingchi People’s HospitalDepartment of Anesthesiology, Nyingchi People’s HospitalAbstract Background Radical or conservative surgical treatment for hepatic Cystic Echinococcosis (hepatic CE) is controversial. We aimed to measure the association between radical surgery (RS) versus conservative surgery (CS) and short-term outcomes in our cohort. Methods Medical records of hepatic CE patients’ demographic, clinical, radiological, operative and postoperative details who underwent surgical treatment between January 3, 2017 and January 3, 2018 at the Department of General Surgery, Nyingchi People's Hospital, Nyingchi, China, were retrieved and analyzed. The primary outcome was overall morbidity. The secondary outcomes included: (i) bile leakage; (ii) complications of lung, pleura, heart, liver, pancreas and biliary tract; (iii) incision infection and residual cavity abscess formation; (iv) anaphylactic reaction and shock; (v) tear of surrounding tissues; (vi) hospital and post-operative length of stay (LOS); (vii) length of surgery; (viii) blood loss during surgery. Multivariable logistic/linear regression models with various adjustment strategies for confounders were performed to evaluate the association. Results A total of 128 hepatic CE patients were included with 82 (64.1%) and 46 (35.9%) receiving CS and RS, respectively. After fully adjusted, RS was associated with 60% lower risk of overall complication (aOR 0.4; 95%CI, 0.2–0.9) and 0.6-h shorter surgical time (aβ 0.4; 95%CI,-0.0–0.8) comparing to CS. However, RS was associated with more blood loss during surgery (aβ 179.3; 95%CI, 54.2–304.5). Conclusion To conclude, RS was associated with a 60% reduction in developing overall complication in the short term, but may result in more blood loss during surgery than CS.https://doi.org/10.1186/s12893-023-02000-yHepatic cystic echinococcosisSurgical procedureLiver resectionEchinococcus granulosusTibet |
| spellingShingle | Liangping Huang Benrong Zheng Aduo Ouzhulamu Xi Li Jianchun Yao Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study BMC Surgery Hepatic cystic echinococcosis Surgical procedure Liver resection Echinococcus granulosus Tibet |
| title | Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study |
| title_full | Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study |
| title_fullStr | Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study |
| title_full_unstemmed | Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study |
| title_short | Association between radical versus conservative surgery and short-term outcomes of hepatic cystic echinococcosis in Nyingchi, China: a retrospective cohort study |
| title_sort | association between radical versus conservative surgery and short term outcomes of hepatic cystic echinococcosis in nyingchi china a retrospective cohort study |
| topic | Hepatic cystic echinococcosis Surgical procedure Liver resection Echinococcus granulosus Tibet |
| url | https://doi.org/10.1186/s12893-023-02000-y |
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