A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T
Purpose: Multichannel Transcranial Magnetic Stimulation (mTMS) [1] is a novel non-invasive brain stimulation technique allowing multiple sites to be stimulated simultaneously or sequentially under electronic control without movement of the coils. To enable simultaneous mTMS and MR imaging, we have d...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2023-07-01
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| Series: | Brain Stimulation |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1935861X23017928 |
| _version_ | 1797738001797742592 |
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| author | Lucia I. Navarro de Lara Jason P. Stockmann Qinglei Meng Boris Keil Azma Mareyam Işıl Uluç Mohammad Daneshzand Sergey Makarov Lawrence L. Wald Aapo Nummenmaa |
| author_facet | Lucia I. Navarro de Lara Jason P. Stockmann Qinglei Meng Boris Keil Azma Mareyam Işıl Uluç Mohammad Daneshzand Sergey Makarov Lawrence L. Wald Aapo Nummenmaa |
| author_sort | Lucia I. Navarro de Lara |
| collection | DOAJ |
| description | Purpose: Multichannel Transcranial Magnetic Stimulation (mTMS) [1] is a novel non-invasive brain stimulation technique allowing multiple sites to be stimulated simultaneously or sequentially under electronic control without movement of the coils. To enable simultaneous mTMS and MR imaging, we have designed and constructed a whole-head 28-channel receive-only RF coil at 3T. Methods: A helmet-shaped structure was designed considering a specific layout for a mTMS system with holes for positioning the TMS units next to the scalp. Diameter of the TMS units defined the diameter of RF loops. The placement of the preamplifiers was designed to minimize possible interactions and to allow straightforward positioning of the mTMS units around the RF coil. Interactions between TMS-MRI were analyzed for the whole-head system extending the results presented in previous publications [2]. Both SNR- and g-factors maps were obtained to compare the imaging performance of the coil with commercial head coils. Results: Sensitivity losses for the RF elements containing TMS units show a well-defined spatial pattern. Simulations indicate that the losses are predominantly caused by eddy currents on the coil wire windings. The average SNR performance of the TMSMR 28-channel coil is about 66% and 86% of the SNR of the 32/20-channel head coil respectively. The g-factor values of the TMSMR 28-channel coil are similar to the 32-channel coil and significantly better than the 20-channel coil. Conclusion: We present the TMSMR 28-channel coil, a head RF coil array to be integrated with a multichannel 3-axisTMS coil system, a novel tool that will enable causal mapping of human brain function. |
| first_indexed | 2024-03-12T13:36:36Z |
| format | Article |
| id | doaj.art-acaffd545ff34e63a73778fc12b28f01 |
| institution | Directory Open Access Journal |
| issn | 1935-861X |
| language | English |
| last_indexed | 2024-03-12T13:36:36Z |
| publishDate | 2023-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Brain Stimulation |
| spelling | doaj.art-acaffd545ff34e63a73778fc12b28f012023-08-24T04:34:45ZengElsevierBrain Stimulation1935-861X2023-07-0116410211031A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3TLucia I. Navarro de Lara0Jason P. Stockmann1Qinglei Meng2Boris Keil3Azma Mareyam4Işıl Uluç5Mohammad Daneshzand6Sergey Makarov7Lawrence L. Wald8Aapo Nummenmaa9Athinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USA; Corresponding author. Athinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Harvard Medical School, Massachusetts General Hospital, 149 13th Street, Charlestown, MA, 02129, USA.Athinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAInstitute of Medical Physics and Radiation Protection, Department of Life Science Engineering, TH Mittelhessen University of Applied Sciences, Giessen, Germany; Department of Diagnostic and Interventional Radiology, University Hospital Marburg, Phillipps University of Marburg, Marburg, GermanyAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USA; Department of Electrical and Computer Engineering at the Worcester Polytechnic Institute, Worcester, MA, 01609, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAAthinoula A. Martinos Center for Biomedical Imaging, Dept. of Radiology, Massachusetts General Hospital, Charlestown, MA, 02129, USA; Harvard Medical School, Boston, MA, 02115, USAPurpose: Multichannel Transcranial Magnetic Stimulation (mTMS) [1] is a novel non-invasive brain stimulation technique allowing multiple sites to be stimulated simultaneously or sequentially under electronic control without movement of the coils. To enable simultaneous mTMS and MR imaging, we have designed and constructed a whole-head 28-channel receive-only RF coil at 3T. Methods: A helmet-shaped structure was designed considering a specific layout for a mTMS system with holes for positioning the TMS units next to the scalp. Diameter of the TMS units defined the diameter of RF loops. The placement of the preamplifiers was designed to minimize possible interactions and to allow straightforward positioning of the mTMS units around the RF coil. Interactions between TMS-MRI were analyzed for the whole-head system extending the results presented in previous publications [2]. Both SNR- and g-factors maps were obtained to compare the imaging performance of the coil with commercial head coils. Results: Sensitivity losses for the RF elements containing TMS units show a well-defined spatial pattern. Simulations indicate that the losses are predominantly caused by eddy currents on the coil wire windings. The average SNR performance of the TMSMR 28-channel coil is about 66% and 86% of the SNR of the 32/20-channel head coil respectively. The g-factor values of the TMSMR 28-channel coil are similar to the 32-channel coil and significantly better than the 20-channel coil. Conclusion: We present the TMSMR 28-channel coil, a head RF coil array to be integrated with a multichannel 3-axisTMS coil system, a novel tool that will enable causal mapping of human brain function.http://www.sciencedirect.com/science/article/pii/S1935861X23017928MTMSSimultaneous TMS/fMRINon-invasive brain stimulationWhole-head RF coil |
| spellingShingle | Lucia I. Navarro de Lara Jason P. Stockmann Qinglei Meng Boris Keil Azma Mareyam Işıl Uluç Mohammad Daneshzand Sergey Makarov Lawrence L. Wald Aapo Nummenmaa A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T Brain Stimulation MTMS Simultaneous TMS/fMRI Non-invasive brain stimulation Whole-head RF coil |
| title | A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T |
| title_full | A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T |
| title_fullStr | A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T |
| title_full_unstemmed | A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T |
| title_short | A novel whole-head RF coil design tailored for concurrent multichannel brain stimulation and imaging at 3T |
| title_sort | novel whole head rf coil design tailored for concurrent multichannel brain stimulation and imaging at 3t |
| topic | MTMS Simultaneous TMS/fMRI Non-invasive brain stimulation Whole-head RF coil |
| url | http://www.sciencedirect.com/science/article/pii/S1935861X23017928 |
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