Alternative 3' pre-mRNA processing in Saccharomyces cerevisiae is modulated by Nab4/Hrp1 in vivo.

Alternative 3' pre-mRNA processing in Saccharomyces cerevisiae is modulated by Nab4/Hrp1 in vivo.

The Saccharomyces cerevisiae RNA-binding protein Nab4/Hrp1 is a component of the cleavage factor complex required for 3' pre-mRNA processing. Although the precise role of Nab4/Hrp1 remains unclear, it has been implicated in correct positioning of the cleavage site in vitro. Here, we show that m...

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Bibliographic Details
Main Authors: Karen S Kim Guisbert, Hao Li, Christine Guthrie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC1717019?pdf=render

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