Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway.

Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway.

Kidney ischemia/reperfusion injury (I/R) is characterized by renal dysfunction and tubular damages resulting from an early activation of innate immunity. Recently, nicotine administration has been shown to be a powerful inhibitor of a variety of innate immune responses, including LPS-induced toxaemi...

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Bibliographic Details
Main Authors: Claude Sadis, Gwen Teske, Geurt Stokman, Carole Kubjak, Nike Claessen, Fabrice Moore, Patrizia Loi, Bilo Diallo, Luc Barvais, Michel Goldman, Sandrine Florquin, Alain Le Moine
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC1867857?pdf=render

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