Primary Bilateral Ovarian Lymphoma: A Rare Case Report
Primary ovarian lymphomas constitute 0.5% of all ovarian malignancies. We report one such case in a middle-aged woman who presented with a bilateral ovarian tumor. Bilateral oophorectomy with salpingectomy was sent for frozen section analysis that revealed a round cell tumor. Final histopathology sh...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Thieme Medical Publishers, Inc.
2022-09-01
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| Series: | Asian Journal of Oncology |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1753497 |
| _version_ | 1811237885932732416 |
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| author | Salwa Bano Veena Ramaswamy Chaitra Chandrashekar |
| author_facet | Salwa Bano Veena Ramaswamy Chaitra Chandrashekar |
| author_sort | Salwa Bano |
| collection | DOAJ |
| description | Primary ovarian lymphomas constitute 0.5% of all ovarian malignancies. We report one such case in a middle-aged woman who presented with a bilateral ovarian tumor. Bilateral oophorectomy with salpingectomy was sent for frozen section analysis that revealed a round cell tumor. Final histopathology showed a mitotically active small round blue cell tumor arranged in diffuse sheets and chords with an evident starry-sky pattern. Extensive immunohistochemistry (IHC) panel was performed. Histopathology along with IHC did not classify the tumor into diffuse-large-B cell-lymphoma or Burkitt lymphoma and a final diagnosis of high-grade B cell lymphoma (HGBL) was made. This case is presented for its rarity and to discuss the challenges on IHC to subclassify a lymphoma as HGBL. Although rare, the possibility of primary ovarian non-Hodgkin lymphoma should be kept in mind when dealing with bilateral ovarian tumors as a timely and accurate diagnosis can save unnecessary surgeries and improve outcome. |
| first_indexed | 2024-04-12T12:32:18Z |
| format | Article |
| id | doaj.art-acba8786baa7489f9be8f05f19f37f9f |
| institution | Directory Open Access Journal |
| issn | 2454-6798 2455-4618 |
| language | English |
| last_indexed | 2024-04-12T12:32:18Z |
| publishDate | 2022-09-01 |
| publisher | Thieme Medical Publishers, Inc. |
| record_format | Article |
| series | Asian Journal of Oncology |
| spelling | doaj.art-acba8786baa7489f9be8f05f19f37f9f2022-12-22T03:33:00ZengThieme Medical Publishers, Inc.Asian Journal of Oncology2454-67982455-46182022-09-01080316016310.1055/s-0042-1753497Primary Bilateral Ovarian Lymphoma: A Rare Case ReportSalwa Bano0Veena Ramaswamy1Chaitra Chandrashekar2Department of Pathology, HCG Cancer Centre, Bengaluru, Karnataka, IndiaDepartment of Pathology, HCG Cancer Centre, Bengaluru, Karnataka, IndiaDepartment of Pathology, HCG Cancer Centre, Bengaluru, Karnataka, IndiaPrimary ovarian lymphomas constitute 0.5% of all ovarian malignancies. We report one such case in a middle-aged woman who presented with a bilateral ovarian tumor. Bilateral oophorectomy with salpingectomy was sent for frozen section analysis that revealed a round cell tumor. Final histopathology showed a mitotically active small round blue cell tumor arranged in diffuse sheets and chords with an evident starry-sky pattern. Extensive immunohistochemistry (IHC) panel was performed. Histopathology along with IHC did not classify the tumor into diffuse-large-B cell-lymphoma or Burkitt lymphoma and a final diagnosis of high-grade B cell lymphoma (HGBL) was made. This case is presented for its rarity and to discuss the challenges on IHC to subclassify a lymphoma as HGBL. Although rare, the possibility of primary ovarian non-Hodgkin lymphoma should be kept in mind when dealing with bilateral ovarian tumors as a timely and accurate diagnosis can save unnecessary surgeries and improve outcome.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1753497primary ovarian lymphomahigh-grade b cell lymphomabilateral ovarian non-hodgkin lymphoma |
| spellingShingle | Salwa Bano Veena Ramaswamy Chaitra Chandrashekar Primary Bilateral Ovarian Lymphoma: A Rare Case Report Asian Journal of Oncology primary ovarian lymphoma high-grade b cell lymphoma bilateral ovarian non-hodgkin lymphoma |
| title | Primary Bilateral Ovarian Lymphoma: A Rare Case Report |
| title_full | Primary Bilateral Ovarian Lymphoma: A Rare Case Report |
| title_fullStr | Primary Bilateral Ovarian Lymphoma: A Rare Case Report |
| title_full_unstemmed | Primary Bilateral Ovarian Lymphoma: A Rare Case Report |
| title_short | Primary Bilateral Ovarian Lymphoma: A Rare Case Report |
| title_sort | primary bilateral ovarian lymphoma a rare case report |
| topic | primary ovarian lymphoma high-grade b cell lymphoma bilateral ovarian non-hodgkin lymphoma |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0042-1753497 |
| work_keys_str_mv | AT salwabano primarybilateralovarianlymphomaararecasereport AT veenaramaswamy primarybilateralovarianlymphomaararecasereport AT chaitrachandrashekar primarybilateralovarianlymphomaararecasereport |