Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system

Malignant pericardial effusions often arise in patients with breаst cancer and ovarian cancer. Sistem antitumor therapy is uneffective in gen- erally and causes side effects. Here we show that intrapericardial interleukin-2 with allogenеc lymphokine-activated killers and interleukin-2 immunotherapy...

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Main Authors: K. S. Titov, S. M. Volkov, L. V. Demidov, A. N. Gritsay, N. I. Lazareva, M. V. Kiselevskiy, A. P. Nikolayev
Format: Article
Language:Russian
Published: ABV-press 2014-07-01
Series:Опухоли женской репродуктивной системы
Subjects:
Online Access:https://ojrs.abvpress.ru/ojrs/article/view/66
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author K. S. Titov
S. M. Volkov
L. V. Demidov
A. N. Gritsay
N. I. Lazareva
M. V. Kiselevskiy
A. P. Nikolayev
author_facet K. S. Titov
S. M. Volkov
L. V. Demidov
A. N. Gritsay
N. I. Lazareva
M. V. Kiselevskiy
A. P. Nikolayev
author_sort K. S. Titov
collection DOAJ
description Malignant pericardial effusions often arise in patients with breаst cancer and ovarian cancer. Sistem antitumor therapy is uneffective in gen- erally and causes side effects. Here we show that intrapericardial interleukin-2 with allogenеc lymphokine-activated killers and interleukin-2 immunotherapy demonstrated the high efficacy in threatment of breаst and ovarian cancer patients with malignant pericardial effusions. The objective effect was 92.3 % аnd 90.0 % accordingly. These results indicates that intrapericardial immunotherapy might be one of the stages of combined treatment of such group of patients. The suggested type of biotherapy increases the survival and life quality of patients.
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spelling doaj.art-acbcba1d10864a0f941029fe597951e72025-03-02T13:05:28ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-07-0103-410110410.17650/1994-4098-2013-0-3-4-101-10481Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive systemK. S. Titov0S. M. Volkov1L. V. Demidov2A. N. Gritsay3N. I. Lazareva4M. V. Kiselevskiy5A. P. Nikolayev6N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowMalignant pericardial effusions often arise in patients with breаst cancer and ovarian cancer. Sistem antitumor therapy is uneffective in gen- erally and causes side effects. Here we show that intrapericardial interleukin-2 with allogenеc lymphokine-activated killers and interleukin-2 immunotherapy demonstrated the high efficacy in threatment of breаst and ovarian cancer patients with malignant pericardial effusions. The objective effect was 92.3 % аnd 90.0 % accordingly. These results indicates that intrapericardial immunotherapy might be one of the stages of combined treatment of such group of patients. The suggested type of biotherapy increases the survival and life quality of patients.https://ojrs.abvpress.ru/ojrs/article/view/66malignant pericardial effusionsbreаst cancerovarian cancerinterleukin-2allogenec lymphokine-activated killersintraperi- cardial immunotherapy
spellingShingle K. S. Titov
S. M. Volkov
L. V. Demidov
A. N. Gritsay
N. I. Lazareva
M. V. Kiselevskiy
A. P. Nikolayev
Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
Опухоли женской репродуктивной системы
malignant pericardial effusions
breаst cancer
ovarian cancer
interleukin-2
allogenec lymphokine-activated killers
intraperi- cardial immunotherapy
title Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
title_full Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
title_fullStr Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
title_full_unstemmed Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
title_short Use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
title_sort use of cellular biotechnologies in treatment metastatic pericarditis at patients with tumors of female reproductive system
topic malignant pericardial effusions
breаst cancer
ovarian cancer
interleukin-2
allogenec lymphokine-activated killers
intraperi- cardial immunotherapy
url https://ojrs.abvpress.ru/ojrs/article/view/66
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