The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.

Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA sub...

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Main Authors: Martha I Nelson, Simon Pollett, Bruno Ghersi, Maria Silva, Mark P Simons, Eliana Icochea, Armando E Gonzalez, Karen Segovia, Matthew R Kasper, Joel M Montgomery, Daniel G Bausch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4718589?pdf=render
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author Martha I Nelson
Simon Pollett
Bruno Ghersi
Maria Silva
Mark P Simons
Eliana Icochea
Armando E Gonzalez
Karen Segovia
Matthew R Kasper
Joel M Montgomery
Daniel G Bausch
author_facet Martha I Nelson
Simon Pollett
Bruno Ghersi
Maria Silva
Mark P Simons
Eliana Icochea
Armando E Gonzalez
Karen Segovia
Matthew R Kasper
Joel M Montgomery
Daniel G Bausch
author_sort Martha I Nelson
collection DOAJ
description Our understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.
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spelling doaj.art-acbfd8159a6c4fa882bea1f59633a52f2022-12-22T00:50:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01111e014605910.1371/journal.pone.0146059The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.Martha I NelsonSimon PollettBruno GhersiMaria SilvaMark P SimonsEliana IcocheaArmando E GonzalezKaren SegoviaMatthew R KasperJoel M MontgomeryDaniel G BauschOur understanding of the global ecology of avian influenza A viruses (AIVs) is impeded by historically low levels of viral surveillance in Latin America. Through sampling and whole-genome sequencing of 31 AIVs from wild birds in Peru, we identified 10 HA subtypes (H1-H4, H6-H7, H10-H13) and 8 NA subtypes (N1-N3, N5-N9). The majority of Peruvian AIVs were closely related to AIVs found in North America. However, unusual reassortants, including a H13 virus containing a PA segment related to extremely divergent Argentinian viruses, suggest that substantial AIV diversity circulates undetected throughout South America.http://europepmc.org/articles/PMC4718589?pdf=render
spellingShingle Martha I Nelson
Simon Pollett
Bruno Ghersi
Maria Silva
Mark P Simons
Eliana Icochea
Armando E Gonzalez
Karen Segovia
Matthew R Kasper
Joel M Montgomery
Daniel G Bausch
The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
PLoS ONE
title The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
title_full The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
title_fullStr The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
title_full_unstemmed The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
title_short The Genetic Diversity of Influenza A Viruses in Wild Birds in Peru.
title_sort genetic diversity of influenza a viruses in wild birds in peru
url http://europepmc.org/articles/PMC4718589?pdf=render
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