Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae)
<i>Carpesium abrotanoides</i> L. (Asteraceae) is a medicinal plant with immense therapeutic importance and bioactivities. It is commonly encountered in various Asian regions. It has numerous ethnomedicinal uses for curing diverse ailments such as toothache, stomach ulcer, boils, tonsilli...
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| Format: | Article |
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MDPI AG
2022-06-01
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| Series: | Plants |
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| author | Sabrin R. M. Ibrahim Sana A. Fadil Haifa A. Fadil Rawan H. Hareeri Hossam M. Abdallah Gamal A. Mohamed |
| author_facet | Sabrin R. M. Ibrahim Sana A. Fadil Haifa A. Fadil Rawan H. Hareeri Hossam M. Abdallah Gamal A. Mohamed |
| author_sort | Sabrin R. M. Ibrahim |
| collection | DOAJ |
| description | <i>Carpesium abrotanoides</i> L. (Asteraceae) is a medicinal plant with immense therapeutic importance and bioactivities. It is commonly encountered in various Asian regions. It has numerous ethnomedicinal uses for curing diverse ailments such as toothache, stomach ulcer, boils, tonsillitis, bronchitis, bacterial infection, bruises, swelling, virus infection, fever, and amygdalitis, as well as an anthelmintic versus round-, tape-, hook-, and pinworms. Different classes of phytoconstituents such as sesquiterpenes, sesquiterpene dimers, monoterpenes, and nitrogenous compounds have been reported from this plant. These phytoconstituents have proved to possess anti-inflammatory, cytotoxic, antimicrobial, and insecticidal capacities. The present review aims to summarize all published data on <i>C. abrotanoides</i> including traditional uses, phytoconstituents, bioactivities, and toxicological aspects, as well as the synthesis and biosynthesis of its metabolites through an extensive survey on various databases and various publishers. These reported data could draw the attention of various natural-metabolite-interested researchers and medicinal chemists towards the development of this plant and/or its metabolites into medicine for the prevention and treatment of certain illnesses. Despite the diverse traditional uses of <i>C. abrotanoides</i>, there is a need for scientific evidence to support these claims. Clinical trials are also required to further assure these data and validate this plant utilization in treating several diseases. |
| first_indexed | 2024-03-09T22:42:47Z |
| format | Article |
| id | doaj.art-acc0365f814444c98ec7eaae705cce4f |
| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-09T22:42:47Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-acc0365f814444c98ec7eaae705cce4f2023-11-23T18:35:08ZengMDPI AGPlants2223-77472022-06-011112159810.3390/plants11121598Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae)Sabrin R. M. Ibrahim0Sana A. Fadil1Haifa A. Fadil2Rawan H. Hareeri3Hossam M. Abdallah4Gamal A. Mohamed5Department of Chemistry, Preparatory Year Program, Batterjee Medical College, Jeddah 21442, Saudi ArabiaDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Clinical and Hospital Pharmacy, Faculty of Pharmacy, Taibah University, Almadinah Almunawarah 30078, Saudi ArabiaDepartment of Pharmacology and Toxicology, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia<i>Carpesium abrotanoides</i> L. (Asteraceae) is a medicinal plant with immense therapeutic importance and bioactivities. It is commonly encountered in various Asian regions. It has numerous ethnomedicinal uses for curing diverse ailments such as toothache, stomach ulcer, boils, tonsillitis, bronchitis, bacterial infection, bruises, swelling, virus infection, fever, and amygdalitis, as well as an anthelmintic versus round-, tape-, hook-, and pinworms. Different classes of phytoconstituents such as sesquiterpenes, sesquiterpene dimers, monoterpenes, and nitrogenous compounds have been reported from this plant. These phytoconstituents have proved to possess anti-inflammatory, cytotoxic, antimicrobial, and insecticidal capacities. The present review aims to summarize all published data on <i>C. abrotanoides</i> including traditional uses, phytoconstituents, bioactivities, and toxicological aspects, as well as the synthesis and biosynthesis of its metabolites through an extensive survey on various databases and various publishers. These reported data could draw the attention of various natural-metabolite-interested researchers and medicinal chemists towards the development of this plant and/or its metabolites into medicine for the prevention and treatment of certain illnesses. Despite the diverse traditional uses of <i>C. abrotanoides</i>, there is a need for scientific evidence to support these claims. Clinical trials are also required to further assure these data and validate this plant utilization in treating several diseases.https://www.mdpi.com/2223-7747/11/12/1598<i>Carpesium abrotanoides</i>Asteraceaesesquiterpenessesquiterpene dimersbioactivitiesbiosynthesis |
| spellingShingle | Sabrin R. M. Ibrahim Sana A. Fadil Haifa A. Fadil Rawan H. Hareeri Hossam M. Abdallah Gamal A. Mohamed Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) Plants <i>Carpesium abrotanoides</i> Asteraceae sesquiterpenes sesquiterpene dimers bioactivities biosynthesis |
| title | Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) |
| title_full | Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) |
| title_fullStr | Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) |
| title_full_unstemmed | Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) |
| title_short | Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of <i>Carpesium abrotanoides</i> L. (Asteraceae) |
| title_sort | ethnobotanical uses phytochemical composition biosynthesis and pharmacological activities of i carpesium abrotanoides i l asteraceae |
| topic | <i>Carpesium abrotanoides</i> Asteraceae sesquiterpenes sesquiterpene dimers bioactivities biosynthesis |
| url | https://www.mdpi.com/2223-7747/11/12/1598 |
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