COVID-19-Associated Liver Injury
Daniel T Gildea,1 Stephanie M Woo,2 Corinne E O’Connor,3 Amol S Rangnekar4 1Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; 2Department of Gastroenterology, MedStar Georgetown University Hospital, Washington, DC, USA; 3Georgetown University School of Med...
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Format: | Article |
Language: | English |
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Dove Medical Press
2023-02-01
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Series: | Hepatic Medicine: Evidence and Research |
Subjects: | |
Online Access: | https://www.dovepress.com/covid-19-associated-liver-injury-peer-reviewed-fulltext-article-HMER |
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author | Gildea DT Woo SM O'Connor CE Rangnekar AS |
author_facet | Gildea DT Woo SM O'Connor CE Rangnekar AS |
author_sort | Gildea DT |
collection | DOAJ |
description | Daniel T Gildea,1 Stephanie M Woo,2 Corinne E O’Connor,3 Amol S Rangnekar4 1Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; 2Department of Gastroenterology, MedStar Georgetown University Hospital, Washington, DC, USA; 3Georgetown University School of Medicine, Washington, DC, USA; 4MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USACorrespondence: Daniel T Gildea, Tel +1 302-985-7777, Email daniel.gildea@medstar.netAbstract: This review analyzes data regarding liver injury associated with COVID-19 infection. We discuss reported effects on the liver from both COVID-19 and COVID-19 treatment as well as pathophysiology, review the potential role of drug-induced liver injury as an etiology of COVID-19-associated liver injury, and touch on other reports of significant outcomes including COVID-19 cholangiopathy and autoimmune hepatitis. Finally, we review the implications of COVID-19 infection in liver transplant recipients.Keywords: COVID-19, cholangiopathy, DILI, hepatitis, transplant, liver |
first_indexed | 2024-04-10T08:54:46Z |
format | Article |
id | doaj.art-acc39c0bb00a4735b39e5a4fbd17d873 |
institution | Directory Open Access Journal |
issn | 1179-1535 |
language | English |
last_indexed | 2024-04-10T08:54:46Z |
publishDate | 2023-02-01 |
publisher | Dove Medical Press |
record_format | Article |
series | Hepatic Medicine: Evidence and Research |
spelling | doaj.art-acc39c0bb00a4735b39e5a4fbd17d8732023-02-21T18:00:14ZengDove Medical PressHepatic Medicine: Evidence and Research1179-15352023-02-01Volume 151981783COVID-19-Associated Liver InjuryGildea DTWoo SMO'Connor CERangnekar ASDaniel T Gildea,1 Stephanie M Woo,2 Corinne E O’Connor,3 Amol S Rangnekar4 1Department of Internal Medicine, MedStar Georgetown University Hospital, Washington, DC, USA; 2Department of Gastroenterology, MedStar Georgetown University Hospital, Washington, DC, USA; 3Georgetown University School of Medicine, Washington, DC, USA; 4MedStar Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC, USACorrespondence: Daniel T Gildea, Tel +1 302-985-7777, Email daniel.gildea@medstar.netAbstract: This review analyzes data regarding liver injury associated with COVID-19 infection. We discuss reported effects on the liver from both COVID-19 and COVID-19 treatment as well as pathophysiology, review the potential role of drug-induced liver injury as an etiology of COVID-19-associated liver injury, and touch on other reports of significant outcomes including COVID-19 cholangiopathy and autoimmune hepatitis. Finally, we review the implications of COVID-19 infection in liver transplant recipients.Keywords: COVID-19, cholangiopathy, DILI, hepatitis, transplant, liverhttps://www.dovepress.com/covid-19-associated-liver-injury-peer-reviewed-fulltext-article-HMERkeywords: covid-19cholangiopathydilihepatitistransplantliver |
spellingShingle | Gildea DT Woo SM O'Connor CE Rangnekar AS COVID-19-Associated Liver Injury Hepatic Medicine: Evidence and Research keywords: covid-19 cholangiopathy dili hepatitis transplant liver |
title | COVID-19-Associated Liver Injury |
title_full | COVID-19-Associated Liver Injury |
title_fullStr | COVID-19-Associated Liver Injury |
title_full_unstemmed | COVID-19-Associated Liver Injury |
title_short | COVID-19-Associated Liver Injury |
title_sort | covid 19 associated liver injury |
topic | keywords: covid-19 cholangiopathy dili hepatitis transplant liver |
url | https://www.dovepress.com/covid-19-associated-liver-injury-peer-reviewed-fulltext-article-HMER |
work_keys_str_mv | AT gildeadt covid19associatedliverinjury AT woosm covid19associatedliverinjury AT oconnorce covid19associatedliverinjury AT rangnekaras covid19associatedliverinjury |