Targeting α-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models

Targeting α-Synuclein in Parkinson's Disease by Induced Pluripotent Stem Cell Models

Parkinson's disease (PD) is a progressive, neurodegenerative disorder characterized by motor and non-motor symptoms. To date, no specific treatment to halt disease progression is available, only medication to alleviate symptoms can be prescribed. The main pathological hallmark of PD is the deve...

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Bibliographic Details
Main Authors:	Angeliki Spathopoulou, Frank Edenhofer, Lisa Fellner
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-01-01
Series:	Frontiers in Neurology
Subjects:	induced pluripotent stem cells α-synuclein Parkinson's disease neurons SNCA triplication SNCA duplication
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2021.786835/full

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