Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012

Background and purpose: Strongyloidiasis is a nematode infection of humans with a worldwide distribution which is more prevalent in tropical and subtropical regions. Infected people are often clinically asymptomatic, however, in untreated immunosuppressed patients, it causes more than 80% mortality....

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Main Authors: Moradali Fouladvand, Afshin Barazesh, Rahim Tahmasebi
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2017-06-01
Series:Journal of Mazandaran University of Medical Sciences
Subjects:
Online Access:http://jmums.mazums.ac.ir/article-1-8651-en.html
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author Moradali Fouladvand
Afshin Barazesh
Rahim Tahmasebi
author_facet Moradali Fouladvand
Afshin Barazesh
Rahim Tahmasebi
author_sort Moradali Fouladvand
collection DOAJ
description Background and purpose: Strongyloidiasis is a nematode infection of humans with a worldwide distribution which is more prevalent in tropical and subtropical regions. Infected people are often clinically asymptomatic, however, in untreated immunosuppressed patients, it causes more than 80% mortality. So, the accurate and timely diagnosis of infection can prevent patient's death. This study was conducted to determine the prevalence of strongyloidiasis in patients under chemotherapy and hemodialysis in Bushehr, Iran. Materials and methods: We performed a cross-sectional study in 2011-2012 in which all chemotherapy and hemodialysis patients were evaluated by ELISA method to determine the presence of anti-Strongyloides stercoralis IgG antibody. Results: A total of 214 individuals were studied from whom 4 (1.9%) patients under chemotherapy and 3 (1.4%) hemodialysis patients were positive for IgG antibody. Conclusion: Strongyloidiasis is as a life-threatening risk factor in people under chemotherapy and hemodialysis, therefore, strongyloidiasis screening is suggested in these patients before administering immunosuppressive drugs, dialysis, and kidney transplant.
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spelling doaj.art-acc68afa463448b58447a0e921dda1ec2023-01-25T07:52:57ZengMazandaran University of Medical SciencesJournal of Mazandaran University of Medical Sciences1735-92601735-92792017-06-0127149187191Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012Moradali Fouladvand0Afshin Barazesh1Rahim Tahmasebi2 Bushehr University of Medical Sciences Bushehr University of Medical Sciences Bushehr University of Medical Sciences Background and purpose: Strongyloidiasis is a nematode infection of humans with a worldwide distribution which is more prevalent in tropical and subtropical regions. Infected people are often clinically asymptomatic, however, in untreated immunosuppressed patients, it causes more than 80% mortality. So, the accurate and timely diagnosis of infection can prevent patient's death. This study was conducted to determine the prevalence of strongyloidiasis in patients under chemotherapy and hemodialysis in Bushehr, Iran. Materials and methods: We performed a cross-sectional study in 2011-2012 in which all chemotherapy and hemodialysis patients were evaluated by ELISA method to determine the presence of anti-Strongyloides stercoralis IgG antibody. Results: A total of 214 individuals were studied from whom 4 (1.9%) patients under chemotherapy and 3 (1.4%) hemodialysis patients were positive for IgG antibody. Conclusion: Strongyloidiasis is as a life-threatening risk factor in people under chemotherapy and hemodialysis, therefore, strongyloidiasis screening is suggested in these patients before administering immunosuppressive drugs, dialysis, and kidney transplant.http://jmums.mazums.ac.ir/article-1-8651-en.htmlstrongyloidiasischemotherapyhemodialysisbushehriran
spellingShingle Moradali Fouladvand
Afshin Barazesh
Rahim Tahmasebi
Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
Journal of Mazandaran University of Medical Sciences
strongyloidiasis
chemotherapy
hemodialysis
bushehr
iran
title Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
title_full Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
title_fullStr Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
title_full_unstemmed Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
title_short Seroepidemiological Study of Strongyloidiasis in Patients Taking Immunosuppressive Drugs in Bushehr, Iran, 2012
title_sort seroepidemiological study of strongyloidiasis in patients taking immunosuppressive drugs in bushehr iran 2012
topic strongyloidiasis
chemotherapy
hemodialysis
bushehr
iran
url http://jmums.mazums.ac.ir/article-1-8651-en.html
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AT afshinbarazesh seroepidemiologicalstudyofstrongyloidiasisinpatientstakingimmunosuppressivedrugsinbushehriran2012
AT rahimtahmasebi seroepidemiologicalstudyofstrongyloidiasisinpatientstakingimmunosuppressivedrugsinbushehriran2012